The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Life-Saving Treatment

by Jessica Wapner

Robert A Weinberg (Foreword)

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Book cover for The Philadelphia Chromosome

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This work discusses the history of a genetic mutation, discovered in 1959, that causes chronic myeloid leukemia, and traces the research and breakthroughs that led to the creation of a drug that makes this once-fatal illness now treatable. It focuses on what is widely viewed as the 'poster child' of rational drug development in the cancer research world. The history of the founding of a genetic mutant chromosome in the indication of Chronic myeloid leukemia disease, and the subsequent development of "Gleevec," is the keynote of this publication.
  • ISBN10 1615191658
  • ISBN13 9781615191659
  • Publish Date 29 April 2014 (first published 14 May 2013)
  • Publish Status Active
  • Publish Country US
  • Imprint Experiment
  • Format eBook
  • Pages 328
  • Language English