Industrial Aspects of Pharmecuticals
High-Performance Liquid Chromatography of Peptides and Proteins
by Colin T. Mant and Robert S. Hodges
Containing articles by internationally renowned scientists, this book covers the use of high performance liquid chromatography (HPLC) techniques for a range of applications. The authors present practical approaches along with clear principles that are easily accessible to the method developer as well as the scientist. They discuss major HPLC analytical modes including size exclusion, ion-exchange, reverse-phase, hydrophobic interactions, immunoaffinity, and more. Highlights of the second edition...
Structure-based Design of Drugs and Other Bioactive Molecules
by Arun K. Ghosh and Sandra Gemma
Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design. This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for...
Powerful Pharmaceutical Sales Guidebook
by Daniel Farb, Professor Bruce Gordon, Susan Postnikoff, and Cynthia Drake
Modern Drug Delivery Systems (Drugs and the Pharmaceutical Sciences)
RNA Towards Medicine
by Volker Erdmann, J rgen Brosius, and hab. Jan Barciszewski
Mutagenic Impurities - Strategies for Identification and Control
by Andrew Teasdale
Learn to implement effective control measures for mutagenic impurities in pharmaceutical development In Mutagenic Impurities: Strategies for Identification and Control, distinguished chemist Andrew Teasdale delivers a thorough examination of mutagenic impurities and their impact on the pharmaceutical industry. The book incorporates the adoption of the ICH M7 guideline and focuses on mutagenic impurities from both a toxicological and analytical perspective. The editor has created a primary refe...
Handbook of SOPs for Good Clinical Practice, Second Edition
by Celine Clive
Completely revised and updated, the second edition of a classic reference, Handbook of SOPs for Good Clinical Practice provides templates of SOPs ready for adaptation to your requirements and immediate use. This allows you to create new SOPs or benchmark your existing SOPs against an internationally accepted set of SOPs. The book includes a CD-ROM containing an electronic copy of each of the SOPs and forms in the handbook so that you can easily customize the text to reflect your organization's p...
Synthetic Multivalent Molecules: Concepts and Biomedical Applications
by Choi
This book provides basic principles of multivalent interactions found in biological systems as well as an up-to-date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. * Contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine * Can be used as both a textbook for students and a reference book for libraries and professionals * Includes detailed case studies * Fills a void in current literature thro...
This book is written to serve as a principal textbook for introductory pharmacogenomics course, emphasizing pedagogy along with applications in a way useful for students along with professionals needing an accessible resource. The text covers each of the important areas of pharmacogenomics - fundamental principles, relevant technologies, clinical applications, and societal issues. It uses diagrams, flow charts, tables and boxed material in each chapter. The author - who himself teaches and desig...
Darkness is Only Light Not Switched on (walking with Angels)
by Jeanne Ames
Schwinghammer's Pharmacotherapy Casebook: A Patient-Focused Approach, Twelfth Edition
by Terry L Schwinghammer
Chemokine Receptors as Drug Targets (Methods and Principles in Medicinal Chemistry)
Lectins and Glycobiology (Springer Laboratory)
The role of lectins and glycoconjugates in various cellular processes is receiving increased interest. Since many cellular glycoconjugates are ligands for lectins, they are used as efficacious tools in biochemistry and cell research. This volume provides all of the relevant techniques to investigate the structure and function of lectins and their various reactions. Included are methods for the preparation of synthetic carbohydrate ligands, the determination of physico-chemical properties of lect...
Nuclear Receptors as Drug Targets (Methods and Principles in Medicinal Chemistry, #39)
Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR, FXR and LXR. Authors from leading pharmaceutical companies around the world present examples and real-life data from their own work.
Drug Testing in Alternate Biological Specimens (Forensic Science and Medicine)
Although the specimen of choice in the US drug testing industry is urine, and serum in clinical medicine, interest has recently grown in the use of other matrices as drug testing media. This book provides researchers and forensic toxicologists with a convenient general text summarizing the state of knowledge today. Chapters focus specifically on the application of these practices to drugs of abuse. The up-to-date information provided is complemented with thorough references.
The Delivery of Regenerative Medicines and Their Impact on Healthcare
Now that prohibitions against stem cell research are relaxing, it is time for the field to move forward with the advances that promise to eliminate so much human suffering. However, it would be naive to ignore the fact that regenerative medicines pose a whole new set of challenges to an industry sector that for decades has geared itself to the development and delivery of traditional pharmaceuticals. Still, significant strides are being made. Unique in its focus, The Delivery of Regenerative Med...
The acousticolateral system plays an important role in the biological activity of vertebrates. It includes the organ of Corty, the vestibular and otolith apparatus, lateral-line organs and electroreceptors. Throughout the acousticolateral system, the sensory receptors are hair cells. Provided here is a comprehensive overview of current research on synaptic transmission in sensory hair cells. Morphological characteristics are presented and data on the properties and selectivity of various ionic c...
Ligand Binding (Methods and Principles in Medicinal Chemistry)
by Gerhard MA1/4ller, Beat Ernst, Raimund Mannhold, Hugo Kubinyi, and Gerd Folkers
A practice-oriented overview of ligand binding modes for medicinal chemists, this handbook systematically surveys classical and non-classical binders and their mechanisms for the most relevant drug target classes, including enzyme, receptors and channels.