The Immortal Life of Henrietta Lacks

by Rebecca Skloot

#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly

NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION

NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. 

Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.

Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. 

Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? 

Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

• ISBN10: 0307589382
• ISBN13: 9780307589385
• Publish Date: 2 February 2010 (first published 1 January 2010)
• Publish Status: Active
• Imprint: Crown Publishing Group (NY)
• Format: Paperback (US Trade)
• Pages: 276
• Language: English

Reviews

[gmcgregor]

In 1951, a 30 year-old black woman, a mother of five, walked into Johns Hopkins and was diagnosed with cervical cancer. She underwent treatment, but didn't survive very long. While she was being treated, a sample was taken of her cervical cells, both the cancerous and non-cancerous ones. Each was cultivated, but while the latter cells died, the former grew and wouldn't stop growing. As was the custom at the time in that lab, the cell line was named after the person it came from: the first two letters of the first name, then the first two of the last. Henrietta Lacks. HeLa. One of the most widely used cell lines in the world for decades, but the person behind it was lost and some people even thought the original donor's name was Helen Lane...until Rebecca Skloot published The Immortal Life of Henrietta Lacks, which told the story of the woman and her descendants for the first time.

Well, "donor" might not have been the correct word to use up there, because Henrietta didn't knowingly "donate" anything. Instead, the doctors working on her took the samples without bothering to ask her permission, which was standard practice at the time. And the ethics of this sort of thing, the evolution of informed consent, is a key part of the book, which Skloot weaves around the story of the Lacks family. How fast medical science has grown, and how slow the field's understanding of or willingness to comply with what is right has been in trying to keep up with it. In a world where all you need to get a basic understanding of your genetic picture is $100, to spit in a tube, and 6-8 weeks for processing, what kind of protections should be around that data? We likely still don't know the full implications of something like that being hacked or leaked.

This book has become a science classic already, and it's easy to see why: Skloot is a talented storyteller, and for most of the book's run does an admirable job of keeping her three pieces (Henrietta herself, the HeLa cells/medical ethics, and the story of the Lacks children) in balance. She does great work in digging up what little information there is about Henrietta's short life, mostly through the connections she managed to build with the children Lacks left behind. I've got some grounding in science research from my days as a psychology student, and I know about some of the more egregious bullshit doctors used to get up to (especially with the poor and people of color), but even I was shocked at how lax regulations on human research used to be and how deeply the focus was on getting data at any costs. I was chilled by the story she recounts of a researcher, who the Lacks children believe was untruthful with them when she encountered them years before the book was written, expressing her longing to be able to get material (i.e. blood) from those same people to perform tests.

The reason I haven't rated this more highly, then, is that it starts to drag at the end, becoming more a story about how the story was reported, which tends to bother me unless it's in small doses. It's clearly rooted in a deep, real fondness for Deborah Lacks, one of her primary sources, and a desire to do justice to her story too...but for me, it didn't have the power of the larger narrative and didn't quite work. That being said, this is a story everyone should read and I definitely recommend it to a wide audience.

[lovelybookshelf]

This is the story of one woman and the incredible cells taken from her, its impact on her family, racism and poverty, the history of medical research and the ethics involved, and the very real human beings behind tissue samples. I did not expect this book to be as compelling and emotional as it was. I listened to the audiobook, which has incredible narration. I was hanging on every word, learned a great deal, and left with much to think about.

[brokentune]

Review to follow.

Probably more of a 3.5* because the book didn't need added emotional manipulation by the author. The story itself was hard-hitting enough.

[Hillary]

http://purplemoonmyst.blogspot.com/2012/01/reviewthe-immortal-life-of-henrietta.html

[Eve1972]

Amazing read!

[kaeta]

Terrific non fiction work on the history of cell cultures and the woman who made it all possible, unbeknownst to her or her family. Read it!

[wyvernfriend]

The story flips between the 1950s of Henrietta Lacks and the late 1990s early 2000s of the authors quest to find the story behind the cells that are so important to modern science, particularly medicine.

Henrietta Lacks was a poor black tobacco farmer in the south. A woman who was sure something was wrong but was ignored at first, and her cells harvested for what she thought was a test about her cancer but turned out to be part of a project to try to get cells to grow. Her cells turned out to be perfect, actually almost too perfect, they are actually invading other cultures!

She died of the cancer, her cells have gone on to be a multi-million dollar industry and her family have never seen anything from it, not even healthcare to any meaningful degree, all they've seen really has been things that have convinced them that indeed the medical industry in the US is discriminatory and cares more about the relationship they have with their famous mother's cells than about them.

It's an indictment of the way people are treated and a sad comment on how one woman, poor, black and ill-treated by life, was so failed during her life but has given so much back to science. A woman they even forgot or called by the wrong name for years. A woman who should never be forgotten.

It's worth the read, even if there are some cringeworthy moments with Henrietta's Daughter Deborah but it does say a lot about the life Henrietta must have led. We can only hope that she will remain remembered and maybe, just maybe, achieve some sort of immortality outside her cells.

[g2pro]

I really enjoyed this one.

[MurderByDeath]

I thought this was an excellent book. The science was excellent. Heartbreaking in it's way though.