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The book provides a fascinating overview about current and sophisticated developments in applied entomology that are powered by molecular biology and that can be summarized under a novel term: insect biotechnology. By analogy with the application of powerful molecular biological tools in medicine (red biotechnology), plant protection (green biotechnology) and industrial processing (white biotechnology), insect biotechnology (yellow biotechnology) provides novel tools and strategies for human we...

The first set of case studies on animal use, this volume offers a thorough, up-to-date exploration of the moral issues related to animal welfare. Its main purpose is to examine how far it is ethically justifiable to harm animals in order to benefit mankind. An excellent introduction provides a framework for the cases and sets the background of philosophical and moral concepts underlying the subject.Sixteen original, previously unpublished essays cover controversies associated with the human use...

The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this ach...

During an interval of 15 years, the Lucille P. Markey Charitable Trust spent over $500 million on four programs in the basic biomedical sciences that support the education and research of graduate students, postdoctoral fellows, junior faculty, and senior researchers. The Markey Trust asked the NRC to evaluate these programs with two questions in mind: a /Were these funds well spent?a and a /What can others in the biomedical and philanthropic communities learn from the programs of the Markey Tr...

`This is an excellent text for anyone wishing to explore the possibilities of a grounded theory approach in management and organizational research. The first two parts ought to be essential reading in methods courses, regardless of the field of investigation′ - Organization Studies `…resources for conducting grounded theory are spread across a number of disciplines… making it difficult for organization and management scholars to track them down. This book describes the grounded theory approach...

This book provides essential worldwide reference information regarding rabies for public health officials, veterinarians, physicians, virologists, epidemiologists, infectious disease specialists, laboratory diagnosticians, and wildlife biologists. The book is divided into six main sections, covering topics such as the rabies virus, including antigenic and biochemical characteristics; pathogenesis, including the immune response to the infection, pathology, and latency; diagnostic techniques; rabi...

Molecular Modeling of Proteins, Second Edition provides a theoretical background of various methods available and enables non-specialists to apply methods to their problems by including updated chapters and new material not covered in the first edition. This detailed volume opens by featuring classical and advanced simulation methods as well as methods to set-up complex systems such as lipid membranes and membrane proteins and continues with chapters devoted to the simulation and analysis of con...

This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and preven...

This book provides information on the latest research from the areas of both developmental toxicology and developmental biology. It covers a wide spectrum of the most powerful techniques currently available for studying the basic parameters of development in vitro and in vivo. The detailed theoretical background allows the critical assessment and application of these techniques. Experimental work in animal systems involves investigations in organisms and at the molecular and cellular level. The...

Biomolecular studies are the trial of Man to understand how Nature manages information at the molecular level. The understanding of molecular informa tion handling in nature is essential for the molecular optimization in chem istry, molecular biology, molecular pharmacology and therefore - as an ex ample - for the development of specifically acting drugs. The famous recent method of technical information management is digital electronics. Over the past few years, evidence has arisen that comp...

Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA's Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Resea

Bernard Rosner's FUNDAMENTALS OF BIOSTATISTICS is a practical introduction to the methods, techniques, and computation of statistics with human subjects. It prepares students for their future courses and careers by introducing the statistical methods most often used in medical literature. Rosner minimizes the amount of mathematical formulation (algebra-based) while still giving complete explanations of all the important concepts. As in previous editions, a major strength of this book is that eve...

Cockroaches offer a useful and inexpensive alternative to traditional laboratory animals, yet most researchers are unfamiliar with their biology. This unique and comprehensive cockroach handbook is written for everyone from novice to expert. It addresses every aspect of cockroach biology, with a particular emphasis on the neuroendocrine system. Liberally illustrated chapters include such topics as cockroach culture, anatomy, behavior, and various experimental techniques. One of the few avail...

This revised edition provides up-to-date protocols developed in the HSC field. A team of leading researchers supply this volume with in-depth, readily reproducible methods for effective characterization of HSC and their developmental potential. The book provides detailed flow cytometry protocols for thorough analysis of enriched HSC populations, and offers a variety of transplantation approaches to measure HSC function in vivo. This is a much needed technical resource in the critically important...

The international cosmetic industry is a highly self-regulated industry that provides quality products with a remarkable absence of toxicity. Specific European Union directives raise the need for quality in vitro methods to yet a new level. These directives will force new practices for safety evaluation of personal care products throughout the world in just a few years. Alternative Methodologies for the Safety Evaluation of Chemicals in the Cosmetic Industry presents a categorization and collec...