Responding to the immense changes due to recent development in research, "Genomes" is the first in a generation of molecular genetics books which combine standard molecular biology with more contemporary genomics. This book focuses on genome organization, expression, replication, and evolution, and includes a description of applications for molecular ecology and anthropology, reflecting the impact of genome biology on other fields of study.
In 1953, James Watson and Francis Crick discovered the double helix structure of DNA. The discovery was a profound, Nobel Prize-winning moment in the history of genetics, but it did not decipher the messages on the twisted, ladderlike strands within our cells. No one knew what the human genome sequence actually was. No one had cracked the code of life. Now, at the beginning of a new millennium, that code has been cracked. Kevin Davies, founding editor of the leading journal in the field, "Natur...
This book explores the many prospects, challenges and ethical questions that surround the engineering of our reproductive cells. It is an accessible, three-part examination, moving from focused, realistic assessments of the promise and problems for this advancing technology to a section of short essays on the implications of our technological ability. Also included is a panel discussion in which leading scientists, ethicists, and public policy workers give voice to their thoughts and concerns re...
Encyclopedia of Medical Genomics and Proteomics, 2 Volume Set (Print)
by Jurgen Fuchs and Maurizio Podda
The Encyclopedia of Medical Genomics and Proteomics offers trail-blazing studies and authoritative contributions from more than 400 specialists on molecular diagnostics, genomics, microbiology, genetics, pharmacogenetics, pathology, forensics, tissue and cell typing, and disease susceptibility. It features coverage of key methods and technologies such as predictive genetic and pharmacogenetic testing and tissue typing for transplantation. It compiles recommendations, research, spanning critical...
Examines the possible source of HIV, analyzing a number of theories concerning its origins and investigating current scientific inquiries into HIV, AIDS, and the search for a cure.
Microarrays Methods and Applications (Nuts and Bolts)
Single Cell Diagnostics (Methods in Molecular Biology, #132) (Methods in Molecular Medicine, #132)
by Alan Thornhill
The aim of "Single Cell Diagnostics: Methods and Protocols" is for all readers to extend their knowledge and expertise in analysis of single cells. The book starts with laser assisted cell collection, non-invasive assessment of single cells and moves through the techniques of standard fluorescence in situ hybridization and polymerase chain reaction (PCR). As the reader moves through the book, the scope and complexity of each technique gradually increases as real-time quantitative PCR, isothermal...
Cloning Systems (Genome Analysis Laboratory Manual S., v. 3)
Methods in Yeast Genetics
by Chris Kaiser, Susan Michaelis, and Aaron Mitchell
Biochemical And Genetic Mechanisms Used By Plant Growth Promoting Bacteria
by Bernard R. Glick, G Holguin, C L Patten, and Donna M Penrose
This book is intended for a wide range of individuals, including scientists, students and informed laypersons who are interested in agricultural biotechnology, alternative agriculture, bioremediation of the environment and decreasing our reliance on pesticides and fungicides. It will deal primarily with understanding, at a biochemical and molecular biological level, how certain free living bacteria are able to promote plant growth; symbiotic bacteria such as Rhizobia will be mentioned only brief...
Analysis of Microarray Gene Expression Data (Trends in Logic)
by Ting Lee Mei-Ling
After genomic sequencing, microarray technology has emerged as a widely used platform for genomic studies in the life sciences. Microarray technology provides a systematic way to survey DNA and RNA variation. With the abundance of data produced from microarray studies, however, the ultimate impact of the studies on biology will depend heavily on data mining and statistical analysis. The contribution of this book is to provide readers with an integrated presentation of various topics on analyzing...
Phospholipid Metabolism in Apoptosis (Subcellular Biochemistry, #36)
by Peter J Quinn and Valerian E. Kagan
The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. It is now well recognised that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The molecular mechanisms of apoptosis are presently unknown and the subject of focused research effort. It is clear that cell membrane structure and properties play an early part in the induction process. Th...
The Cytoskeleton (Colloquium der Gesellschaft fur Biologische Chemie in Mosbach Baden, #45)
This volume contains the proceedings of the 45th Mosbach Colloquium of the German Society for Biological Chemistry (GBCh). The 1994 meeting was the first in this series devoted to the cytoskeleton. This complex system enables the eukaryotic cell to form discrete contacts with neighboring cells and the extracellular matrix, to differentiate, to move, change shape, transport organelles, and proliferate. These diverse tasks are performed by three distinct fibrillar networks: microfilaments, microtu...
Epigenetic Principles of Evolution (Elsevier Insights)
by Nelson R. Cabej
This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic "user" of the "genetic toolkit", this book demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties. The author convincingly supports his theory with a host of examples from the most varied fields of biology, by emphasizing changes in developmental pathways as the basic source of evolutionary change in me...
This FISH application guide provides an overview of the principles and the basic techniques of fluorescence in situ hybridization (FISH) and primed in situ hybridization (PRINS), which are successfully used to study many aspects of genomic behavior and alterations. In 36 chapters, contributed by international experts in their particular field, the nowadays multiple approaches and applications of the powerful techniques are presented and detailed protocols are given. Described here are methods us...
Medizin- Und Bioethik (Ethik Transdisziplinar, #1) (Ethik Transdisziplinaer, #1)
Diese umfassende und interdisziplinare Bestandsaufnahme zur Medizin- und Bioethik will den Denkanstoss liefern zu einer gemeinsamen politischen, sozialen, rechtlich und naturwissenschaftlich verankerten Verortung des kunftigen Gesundheitswesens. Der Praxisbezug fur das Wohl des Einzelnen steht im Vordergrund. Dabei ergeben sich Spannungsfelder, dramatische wirtschaftsethische Fragen im Verhaltnis von Forschung, Verantwortung und Haftung. Transplantation, Patientenverfugung, Sterben und Tod, Mitt...
Study Guide and Solutions Manual for Genetic Analysis
by Mark F. Sanders, John L. Bowman, and Peter Mirabito
Written by Peter Mirabito from University of Kentucky, the Study Guide/Solutions Manual is divided into five sections: Genetics Problem-Solving Toolkit, Types of Genetics Problems, Solutions to End-of-Chapter Problems, and Test Yourself. In the "toolkit," students are reminded of key terms and concepts and key relationships that are needed to solve the types of problems in a chapter. This is followed by a breakdown of the types of problems students will encounter in the end of chapter problems f...
Class 3.1 Hydrolases V (Springer Handbook of Enzymes, #10)
The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes...
Confronted by challenges from conservative governments and an array of new economic and ideological forces, the once strong labor movement project of social emancipation is today plagued by serious doubt and confusion. This book discusses how the labor and social movements can best overcome these challenges, examining the Social Democratic heritage; the concept of associative democracy; the "democratization" of capital, industry, technology, and social programs; and the future of trade unions, t...
Many people assume that eugenics all but disappeared with the fall of Nazism, but as this sweeping history demonstrates, the idea of better breeding had a wide and surprising reach in the United States throughout the twentieth century. With an original emphasis on the American West, "Eugenic Nation" brings to light many little-known facts - for example, that one-third of the involuntary sterilizations in this country occurred in California between 1909 and 1979 - as it explores the influence of...