There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in person...
The Information Revolution: Impact on Science and Technology (Data and Knowledge in a Changing World)
J.-E. Dubois and N. Gershon This book was inspired by the Symposium on "Communications and Computer Aided Systems" held at the 14th International CODATA Conference in September 1994 in Chambery, France. It was conceived and influenced by the discussions at the symposium and most of the contributions were written following the Conference. This is the first comprehensive book, published in one volume, of issues concerning the challenges and the vital impact of the information revolution (including...
Nuclear ftedicine is not and has not been a purely imaging discipline. It is function analysis that has always been the focal pOint. This fact has become particularly obvious in the last few years through the employment of nev short-lived radionuclides, new technical procedures and data processing. The disadvantage of function analysis in Inclear ftedicine through the use of radioactively labeled compounds is that more and more complicated and expensive equipment his to be used. A further charac...
Compiled by the OFFICE FOR NATIONAL STATISTICS, this annual review offers a detailed insight into stillbirths, infant and perinatal deaths. It analyses key risk factors involved and provides information on areas such as social class, the age of the mother, and birthweight.
Score your highest in biostatistics Biostatistics is a required course for students of medicine, epidemiology, forestry, agriculture, bioinformatics, and public health. In years past this course has been mainly a graduate-level requirement; however its application is growing and course offerings at the undergraduate level are exploding. Biostatistics For Dummies is an excellent resource for those taking a course, as well as for those in need of a handy reference to this complex material. Biostat...
This book builds a much-needed bridge between biostatistics and organismal biology by linking the arithmetic of statistical studies of organismal form to the biological inferences that may follow from it. It incorporates a cascade of new explanations of regression, correlation, covariance analysis, and principal components analysis, before applying these techniques to an increasingly common data resource: the description of organismal forms by sets of landmark point configurations. For each data...
This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the...
Am 3. und 4. Marz 1982 fand an der Freien Universitat Berlin eine Ar- beitstagung mit dem Thema "Erfahrungen mit dem Anwendungsfach Medizin im Rahmen eines Informatikstudiums" statt. Eingeladen hatte hierzu der FachausschuB 14 "Anwendungen in der Medi- zin" der Gesellschaft fUr Informatik (GI); und unterstUtzt wurde die Veranstaltung von dem Fachbereich Medizinische Informatik der Gesell- schaft fUr Medizinische Dokumentation, Informatik und Statistik (GMDS). Teilnehmer waren Dozenten, Absolvent...
Strategische Analyse der sekundären Hypertonieprävention
by K Heidenberger
Einsatz von Datenbanksystemen (Informationstechnik und Datenverarbeitung)
by Martin Durr and Klaus Radermacher
Dieses Buch stellt den Einsatz von Datenbanksystemen in realen Anwendungen vor und vermittelt die für den Praktiker notwendigen Grundkenntnisse über die bedeutendsten Datenmodelle - das Netzwerkmodell und das relationale Modell - und den Datenbankentwurf. Die verwendeten Datenbasen entsprechen in Komplexität und Größe durchaus der betrieblichen Praxis. Der Leser wird so mit handwerklichen Fähigkeiten vertraut gemacht, die sich unmittelbar in die Praxis umsetzen lassen. Jedem Kapitel ist ein Absc...
Single-Arm Phase II Survival Trial Design (Chapman & Hall/CRC Biostatistics)
by Jianrong Wu
Single-Arm Phase II Survival Trial Design provides a comprehensive summary to the most commonly- used methods for single-arm phase II trial design with time-to-event endpoints. Single-arm phase II trials are a key component for successfully developing advanced cancer drugs and treatments, particular for target therapy and immunotherapy in which time-to-event endpoints are often the primary endpoints. Most test statistics for single-arm phase II trial design with time-to-event endpoints are not a...
Methodological Developments in Data Linkage (Wiley Series in Probability and Statistics)
by Katie Harron, Harvey Goldstein, and Chris Dibben
A comprehensive compilation of new developments in data linkage methodology The increasing availability of large administrative databases has led to a dramatic rise in the use of data linkage, yet the standard texts on linkage are still those which describe the seminal work from the 1950-60s, with some updates. Linkage and analysis of data across sources remains problematic due to lack of discriminatory and accurate identifiers, missing data and regulatory issues. Recent developments in data lin...
This set contains the text Fundamentals of Quality Control and Improvement, 3rd Edition 9780470226537 and Fundamentals of Quality Control and Improvement, 3rd Edition, Student Solutions Manual 9780470256978.
This reference book on clinical experimentation focuses on principles that are especially useful in the design and analysis of studies on human subjects. It shows how to choose between modern and classical competing designs for a clinical study - such as crossover designs, multicenter studies, and repeated measure experiments - how to carry out each design and analyze the resulting data. The book provides many practical examples, end-of-chapter problems and references, and solutions to each prob...
Cambridge Dictionary of Statistics in the Medical Sciences
by Brian S Everitt
If you use statistics and need a useful, up-to-date and reliable sourcebook that provides simple definitions and explanations of statistical concepts, especially those used in biomedicine, then you will need this 1995 dictionary. Over 2000 terms are included here; Professor Everitt has aimed to provide brief but useful descriptions of those terms frequently found in the medical and medical statistics literature. Where appropriate, graphical illustrations or numerical examples are given, and the...
Medizinische Statistik für Dummies (Fur Dummies)
by Geraldine Rauch, Jochen Kruppa, Ulrike Grittner, Konrad Neumann, and Carolin Herrmann
Wenn auch Sie Ihre kleinen Problemchen mit medizinischer Statistik haben, sind Sie hier genau richtig. Mit viel Witz bringen Ihnen die Autoren Geraldine Rauch, Konrad Neumann, Ulrike Grittner, Carolin Herrmann und Jochen Kruppa die Prinzipien der Biostatistik näher. In diesem Buch lernen Sie alles, was Sie benötigen, um Statistik im medizinischen Bereich erfolgreich einzusetzen. Angefangen bei der Begriffskunde und den Grundlagen, erfahren Sie alles von Studientypen über deskriptive Verfahren, V...
The Statistics of Gene Mapping (Statistics for Biology and Health)
by David Siegmund and Benjamin Yakir
This book details the statistical concepts used in gene mapping, first in the experimental context of crosses of inbred lines and then in outbred populations, primarily humans. It presents elementary principles of probability and statistics, which are implemented by computational tools based on the R programming language to simulate genetic experiments and evaluate statistical analyses. Each chapter contains exercises, both theoretical and computational, some routine and others that are more cha...
Analysis of Variance and Covariance
by C. Patrick Doncaster and Andrew J. H. Davey
Analysis of variance (ANOVA) is a core technique for analysing data in the Life Sciences. This reference book bridges the gap between statistical theory and practical data analysis by presenting a comprehensive set of tables for all standard models of analysis of variance and covariance with up to three treatment factors. The book will serve as a tool to help post-graduates and professionals define their hypotheses, design appropriate experiments, translate them into a statistical model, validat...
Packed with worked examples and problems, this book will help the reader improve their confidence and skill in data-handling. The mathematical methods needed for problem-solving are described in the first part of the book, with chapters covering topics such as indices, graphs and logarithms. The following eight chapters explore data-handling in different areas of microbiology and biochemistry including microbial growth, enzymes and radioactivity. Each chapter is fully illustrated with worked exa...
Handbook of Quantitative Forest Genetics (Forestry Sciences, #39)
This handbook was designed as a reference tool for forest geneticists, tree breeders and other tree improvement personnel, as well as a textbook for university courses and short-courses at the graduate level in quantitative genetics. The chapters focus on the decision points faced by quantitative geneticists and breeders in designing programs and analyzing data. Beginning with a justification for the use of quantitative genetics in decision making in tree improvement programs, the book...
This textbook for a second course in basic statistics for undergraduates or first-year graduate students introduces linear regression models and describes other linear models including Poisson regression, logistic regression, proportional hazards regression, and nonparametric regression. Numerous examples drawn from the news and current events with an emphasis on health issues illustrate these concepts. Assuming only a pre-calculus background, the author keeps equations to a minimum and demonstr...