An Introduction to Adaptive Designs with Applications to Clinical Trials Using R (Statistics in Practice)

by Michael R Chernick and Kenneth N. Anderson

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This book presents an up-to-date, accessible, and authoritative look into the rapidly emerging study of statistical adaptive design. Employing the R language throughout, it emphasizes the usefulness of adaptive design methods and technology in public health and research settings through practical examples and plentiful exercises. Special focus is on adaptive late-stage clinical trial designs as extensions of the highly successful group sequential methods that have been applied for more than two decades. It is the first elementary text on the subject matter that is aimed at clinicians, investigators, credit rating analysts, medical writers, regulatory affairs specialists, and applied statisticians.
  • ISBN10 0470404450
  • ISBN13 9780470404454
  • Publish Date 5 June 2009
  • Publish Status Cancelled
  • Publish Country US
  • Publisher John Wiley and Sons Ltd
  • Imprint Wiley-Blackwell