EGFR-Directed Therapy in Lung Cancer (Elements in Molecular Oncology)
by So-Yeon Kim, Daniel B. Costa, Daisuke Shibahara, Susumu Kobayashi, and Balazs Halmos
Epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) is a clinically important driver alteration affecting approximately one-third of lung cancer patients. Treatments for EGFR-exon 19 deletion and exon 21 L858R NSCLC have evolved over the last decade from first-generation reversible tyrosine kinase inhibitors (TKI) to third-generation irreversible TKIs, of which osimertinib has been the widely accepted as first-line therapy. Despite survival improvement seen with osi...
100 Questions & Answers about Head and Neck Cancer
by Elise Carper, Kenneth S Hu, and Elena Kuzin
Prostatakarzinom (Multimediale Bibliothek Der Medizin / Springer Symposia Live)
DeLayne and Chris Haga’s lives change in an instant when he is diagnosed with stage IV lung cancer. He had never smoked. Learn from this diligent caregiver’s experiences as she proactively advocates for her husband to save his life. Join this spiritual journey as faith, hope, and love carry the Hagas through their difficult six-year roller coaster of challenges in this beautifully honest personal story. Witness how God works through a seemingly impossible situation to help Chris gain victory...
OncoLink Patient Guide
This book provides you with the essential information that you will need throughout all stages of this disease. Avoiding jargon, it answers all the questions that you have concerning risk and prevention, screening and diagnosis, through to all the various treatment options available: surgery, chemotherapy, targeted therapies, radiation and hormonal therapy, complementary and alternative therapies and provides you with day-to-day lifestyle advice too.
Metastasis (Novartis Foundation Symposia, #141)
An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially invasive processes--and inhibitors that might prevent metastasis. Also discusses determination of the metastatic genotype, the role of the immune system, and reduction of metastasis via liposome-activated macrophages.
I Refused Chemo shows those diagnosed with cancer what to do next with 7 steps to taking back their power and healing their Lymphoma. A cancer diagnosis can feel like a death sentence. It can be a very scary, dark, and lonely place. After being diagnosed with a form of Hodgkin’s Lymphoma (nLPHL), cancer and life coach Teri Dale refused to go along with the toxic treatments strongly recommended by her oncologist. Instead, she researched holistic, natural alternatives for a cure—and was able to he...
Most women pay little attention to their breasts unless there is a problem. The Secret of Health: Breast Wisdom changes that focus from illness to wellness and provides specific ways women can create and sustain breast health throughout their lives. This book presents a unique approach that stems from the principles of the Law of Attraction as presented in the blockbuster movie, The Secret, in which Dr. Johnson appears. The Secret of Health: Breast Wisdom expands on the Law of Attraction by addi...
A trip to France awakens the past in this heartwarming short summer read from the author of People We Love.Headteacher Nicola Arnott prides herself on her independence. She has successfully juggled motherhood and career, coping with early widowhood by burying her emotions somewhere deep inside herself. When a cancer scare shakes her out of her careful approach to life, she finds herself thinking wistfully of her first love, a young French medical student.She decides to revisit the sleepy French...
The Chemistry and Biology of Benz[a]anthracenes (Cambridge Monographs on Cancer Research)
by M. S. Newman, B. Tierney, and S. Veeraraghavan
First published in 1988, this volume surveys the chemical synthesis and biological activity of the benz[a]anthracenes. These compounds occur in smoke and mineral oils and a few have been shown to be potent carcinogens. This volume was the first to review, systematically and in depth, the organic synthesis of these compounds as well as their metablolism, interactions with nucleic acids and protein, mutagenicity and carcinogenicity. Such studies have important implications in determining mechanism...
There are countless academic books on the subject of childhood leukemia. The idea behind this book, however, is very different. Here, we look at the extraordinary story of childhood leukemia from very distinct and unique perspectives: a distinguished physician who has lived through the transition of the disease from despair to success (and who played a key role in the latter); a distinguished laboratory scientist who has helped breach the barrenness of biological ignorance of the disease to reve...
Rethinking Cancer (Vienna Theoretical Biology) (Vienna Series in Theoretical Biology)
Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new t...
The Rubber Industry (IARC Monographs, v. 28)
by The International Agency for Research on Cancer
Some aziridines, N-, S- and O- mustards and selenium (IARC Monographs, v. 9)
by The International Agency for Research on Cancer
Natural Terpenoids as Messengers
by Paul Harrewijn, Adriaan M. van Oosten, and Paul G. M. Piron
In contrast to books on specific bioactive compounds, this book deals with the role of mevalonic acid metabolites (isoprenoids and their derived structures) in metabolism, development, and functions of organisms, which, though diverse, show various levels of communication. Different disciplines are brought together in a discussion of the messenger functions of terpenoids within and between organisms belonging to five biological kingdoms: bacteria, fungi, plants, insects, and vertebrates (...
Tell Me What to Eat to Help Prevent Colon Cancer
by Elaine Moquette-Magee
DNA Methylation
DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between arti...
A three-time cancer survivor shares her belief that greater understanding of the mind-body connection helped her beat cancer when her doctors thought all hope was lost, in a book that includes stories of similar survivors who leveraged such alternative therapies as improved nutrition, supplements and the healing power of the subconscious mind. Original.
Ultraviolet Radiation in the Solar System (Astrophysics and Space Science Library, #331)
by M Vazquez and A Hanslmeier
In the history of science the opening up of a new observational or experimental window is always followed by an increase in knowledge of the subject concerned. This is also the case with the subject of this book, ultraviolet radiation (hereafter UV). In principle, the ultraviolet range might be just one more of these windows, of no particular importance. However, the energy per UV photon provides the main peculiarity, its magnitude being great enough to produce important ch- ical reactions in th...
The Golgi apparatus (GA) is typically comprised of a series of five to eight cup-shaped, membrane-covered sacs called cisternae that look something like a stack of deflated balloons. The GA is often considered the "distribution and shipping department" for the cell's chemical products. This book traces the first 100 years of GA discovery from the first published accounts from Pavia, Italy, in 1898 to the Centenary Celebration in Pavia, Italy, in 1998 to our most recent discoveries. It summarizes...