DNA Methylation: Approaches, Methods, and Applications

Manel Esteller (Editor), Carmen Jeronimo, Susan J. Clark, Rainer Claus, M. Luebbert, Jens Hasskarl, Henrique Rui, Maria Strazzullo, Maria Rosaria Matarazzo, Maurizio D'Esposito, Jonathan Cheng, Daniel J. Weisenberger, Peter Jones, Nicole M. Sodir, Peter W. Laird, Donimic J. Smiraglia, Christoph Plass, Joseph F. Costello, and Laura J. Rush

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DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological perspectives on DNA methylation. This is an invaluable handbook for researchers and clinicians interested in genetics and molecular biology, particularly epigenetic therapies and gene silencing.
  • ISBN10 084932050X
  • ISBN13 9780849320507
  • Publish Date 29 September 2004
  • Publish Status Active
  • Publish Country US
  • Publisher Taylor & Francis Inc
  • Imprint CRC Press Inc
  • Format Hardcover
  • Pages 240
  • Language English