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Clinical trials tasks and activities are widely diverse and require certain skill sets to both plan and execute. This book provides professionals in the field of clinical research with valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It discusses key obstacles such as challenges to patient recruitment, investigator and study site selection, and dealing with compliance issues. Through practical...

This book relates to the analysis and the development of methods to for a nerve-machine interface. Peripheral nerves, both somatic and autonomic, carry signals related to control and the status of the organs. Nerves are made up of many fascicles, each surrounded by protective membranes. The goal is to provide a theoretical and experimental understanding of how one can recover neural signals from the various fascicles or selectively control the activation of these fascicles.

Statistical Approaches in Oncology Clinical Development : Current Paradigm and Methodological Advancement presents an overview of statistical considerations in oncology clinical trials, both early and late phase of development. It illustrates how novel statistical methods can enrich the design and analysis of modern oncology trials. The authors include many relevant real life examples from the pharmaceutical industry and academia based on their first-hand experience. Along with relevant referenc...

Diagnosis is a practically-oriented guide to the complex reasoning, observations, and judgment that health professionals draw on to make a clinical diagnosis. Built on the cornerstone of the patient-physician relationship, this volume combines rigorous yet accessible conceptual analysis with actionable strategies for navigating uncertainty, making effective use of diagnostic tests, and understanding the economic, interpersonal, and ethical considerations influencing diagnosis. Across six chapter...

¿No se siente bien El reconocido experto en pulmones, Neil Schachter, M.D., le darÁ toda la informaciÓn que necesita para fortalecer su sistema inmunolÓgico y evitar enfermarse. Y en el caso desafortunado de que sÍ tenga una gripe o un resfriado, sabrÁ exactamente quÉ hacer para aliviar los incÓmodos sÍntomas de congestiÓn y fiebre. En este libro encontrarÁ:Tratamientos para las infecciones respiratorias mÁs comunes como la gripe, los resfriados, la bronquitis, la neumonÍa, la sinusitis o el e...

Research Ethics for Scientists A fully updated textbook helping advanced students and young scientists navigate the ethical challenges that are common to scientific researchers in academia As the number of scientific journals, government regulations, and institutional guidelines continue to grow, research scientists are increasingly facing ethical dilemmas. Even seasoned and honest scientists can unintentionally commit research misconduct or fail to detect and address intentional misbehavior....

It is estimated that there are up to 30 strokes every minute throughout the world.* A stroke can be fatal or disabling, while others are purely temporary with a recovery time of less than 24 hours. Whatever the case, a stroke is always serious and as well as having physical and mental consequences for the sufferer, it can also have a significant effect on other family members. This book gives the basic information needed to understand what a stroke is, how to spot the risk factors that may...