Vol 17

Methods in Neurosciences

Published 22 October 1993
Recent data suggest a critical role for cytokines in the regulation of brain and endocrine ftmction under non-nal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the endocrine system. Major topics include: General aspects of cvtokines, including the endoizenous agonists and antagonists, their receptors, @heir second messengers, and transport mechanisms for c@lokines across the blood-brain barr' ler The anatomical localization of cytokines, cytokine receptors, and their respective niRNA in brain and in endocrine tissues Methods for evaluating the in vivo and in vitro actions of cytokines on hormone secretion