Volume 8 begins with a detailed description of the functional anatomy of the various regions and critical cells of the respiratory tract, from the nasal cavity to the gas exchange region. This section conveys the structural heterogeneity of the respiratory system and how it determines tissue and cellular targets for toxic agents. The next section describes functional and biochemical responses of the lungs to toxic insult and includes chapters on carcinogenic and developmental responses to chemical exposure. The final section comprises over 20 chapters describing injurious effects of selected chemicals of toxicologic interest. Human health concerns as well as mechanisms of toxicity are emphasized. Unlike other volumes that have treated this subject, attention is devoted to effects of toxic agents on both the airways and the pulmonary vasculature.
- ISBN13 9780080429731
- Publish Date 4 August 1999
- Publish Status Withdrawn
- Out of Print 7 November 2009
- Publish Country GB
- Publisher Elsevier Science & Technology
- Imprint Pergamon Press
- Format Hardcover
- Pages 657
- Language English