Focusing on an integral part of pharmaceutical development, Sample Size Calculations in Clinical Research, Second Edition presents statistical procedures for performing sample size calculations during various phases of clinical research and development. It provides sample size formulas and procedures for testing equality, noninferiority/superiority, and equivalence.A comprehensive and unified presentation of statistical concepts and practical applications, this book highlights the interactions between clinicians and biostatisticians, includes a well-balanced summary of current and emerging clinical issues, and explores recently developed statistical methodologies for sample size calculation. Whenever possible, each chapter provides a brief history or background, regulatory requirements, statistical designs and methods for data analysis, real-world examples, future research developments, and related references.
One of the few books to systematically summarize clinical research procedures, this edition contains new chapters that focus on three key areas of this field. Incorporating the material of this book in your work will help ensure the validity and, ultimately, the success of your clinical studies.
- ISBN10 1584889829
- ISBN13 9781584889823
- Publish Date 22 August 2007
- Publish Status Unknown
- Out of Print 15 June 2021
- Publish Country US
- Publisher Taylor & Francis Ltd
- Imprint Chapman & Hall/CRC
- Edition 2nd New edition
- Format Hardcover
- Pages 480
- Language English