Dead Ends and Detours: Direct Ways to Successful Total Synthesis

by Miguel A. Sierra and Maria C. de la Torre

K. C. Nicolaou (Foreword)

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A plethora of publications provide valuable information for the organic chemist, yet the results are almost always based on successful reactions. However, a chemist's life is unfortunately not that easy. On the contrary, trial and error is still one of the most commonly used methods. Thus it would be useful to have access to those syntheses that do not work, since they also provide important results of great importance for further synthesis.
This long-awaited book by M. A. Sierra and M. C. de la Torre fills just such a gap. Using major total syntheses they explain the most varied problems and recommend ways out of such dilemmas: Problems at the start and end of a synthesis, difficult and unexpected reactivities of functional groups, problems due to steric properties and much more.
The result is a true wealth of information for any organic chemist. The essential tool for successful total synthesis.
  • ISBN10 3527306447
  • ISBN13 9783527306442
  • Publish Date 26 November 2004
  • Publish Status Active
  • Publish Country DE
  • Publisher Wiley-VCH Verlag GmbH
  • Imprint Blackwell Verlag GmbH
  • Format Paperback
  • Pages 290
  • Language English