Modeling and Analysis of Shape with Applications in Computer-Aided Diagnosis of Breast Cancer (Synthesis Lectures on Biomedical Engineering)

by Denise Guliato and Rangaraj Rangayyan

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Malignant tumors due to breast cancer and masses due to benign disease appear in mammograms with different shape characteristics: the former usually have rough, spiculated, or microlobulated contours, whereas the latter commonly have smooth, round, oval, or macrolobulated contours. Features that characterize shape roughness and complexity can assist in distinguishing between malignant tumors and benign masses. In spite of the established importance of shape factors in the analysis of breast tumors and masses, difficulties exist in obtaining accurate and artifact-free boundaries of the related regions from mammograms. Whereas manually drawn contours could contain artifacts related to hand tremor and are subject to intra-observer and inter-observer variations, automatically detected contours could contain noise and inaccuracies due to limitations or errors in the procedures for the detection and segmentation of the related regions. Modeling procedures are desired to eliminate the artifacts in a given contour, while preserving the important and significant details present in the contour.
  • ISBN10 1608450333
  • ISBN13 9781608450336
  • Publish Date 2 February 2011
  • Publish Status Active
  • Imprint Morgan & Claypool
  • Format eBook
  • Pages 95
  • Language English