Researchers from both industry and academia present in detail techniques for the extraction and isolation of natural products of all classes. These experienced experimentalists describe a wide array of methodologies, including basic chromatography, ion-exchange methods, HPLC, countercurrent and planar chromatography, SFE, and crystallization. They also address the specific problems involved in working with plants, marine organisms, water-soluble compounds, scale-up, dereplication and partial identification, and follow-up of a natural product lead. For the less-experienced they offer hands-on advice - using real examples - about how to approach an extraction in general, when and why to apply a particular technique, how to carry out the methods described, and how to modify conditions according to the compound being isolated.
- ISBN10 0896033627
- ISBN13 9780896033627
- Publish Date 1 January 1998
- Publish Status Active
- Out of Print 23 March 2008
- Publish Country US
- Imprint Humana Press Inc.
- Format Paperback
- Pages 480
- Language English