Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment (ACS Symposium, #1099)

James P Knaak (Editor), Charles Timchalk (Editor), and Rogelio Tornero-Velez (Editor)

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Book cover for Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment

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The metabolism of modern agrochemicals in animals, plants, and the environment have been extensively studied and reported in the literature by scientists. The results of a considerable number of these studies have been presented at National ACS, AGRO Division meetings and eventually published in the Journal of Agricultural and Food Chemistry, the ACS Symposium Series, as well as other ACS journals and books. These studies support the current registrations and use of
pesticides in the United States and worldwide. The integration of metabolism and toxicological studies in assessing human risks to pesticides is best performed using predictive physiological pharmacokinetic/pharmacodynamic and QSAR models. Physiological, biochemical, and toxicological parameters are
required for model development and is the subject of the chapters in this book. The book will update the scientific community in the development of the parameters required by pesticide PBPK/PD models and their application in model development, simulation, and risk assessment.
  • ISBN10 0841226458
  • ISBN13 9780841226456
  • Publish Date 14 March 2013
  • Publish Status Transferred
  • Publish Country US
  • Imprint Oxford University Press Inc
  • Format Hardcover
  • Pages 368
  • Language English