Storing Clocked Programs Inside DNA (Synthesis Lectures on Computer Science)
by Jessica Chang and Professor of Computer Science Dennis Shasha
In the history of modern computation, large mechanical calculators preceded computers. A person would sit there punching keys according to a procedure and a number would eventually appear. Once calculators became fast enough, it became obvious that the critical path was the punching rather than the calculation itself. That is what made the stored program concept vital to further progress. Once the instructions were stored in the machine, the entire computation could run at the speed of the machi...
Biologically Inspired Robotics
Robotic engineering inspired by biology-biomimetics-has many potential applications: robot snakes can be used for rescue operations in disasters, snake-like endoscopes can be used in medical diagnosis, and artificial muscles can replace damaged muscles to recover the motor functions of human limbs. Conversely, the application of robotics technology to our understanding of biological systems and behaviors-biorobotic modeling and analysis-provides unique research opportunities: robotic manipulatio...
The boundaries between simple and complicated, and complicated and complex system designations are fuzzy and debatable, even using quantitative measures of complexity. However, if you are a biomedical engineer, a biologist, physiologist, economist, politician, stock market speculator, or politician, you have encountered complex systems. Furthermore, your success depends on your ability to successfully interact with and manage a variety of complex systems. In order not to be blindsided by unexpec...
Therapies for regenerating damaged tissue and organs have been attracting much attention. In order to efficiently regenerate the functions of living tissue and organs, diverse attempts have been made to utilize scaffolds to “mold” artificial tissue structures. However, the structural complexity of reconstituted tissue is limited by the mechanical precision of scaffolds, which still cause problems arising from their degradation, immunogenic reactions, and so forth. It is also being realized that...
Flow Cytometry (NATO ASI, v. 67)
Described here are the practical applications of flow cytometry in specific biological systems, ranging from cell biology to chromosome analysis and sorting. Three major areas of interest in cell and molecular biology are addressed: - Cell Activation and Biological Response. - Membrane-Ligand Interactions and Cell Identity. - Nuclear Components: Form and Function. Data management, expert systems and cell sorting techniques concerning all aspects of flow cytometry are also presented.
Microbes in Agri-Forestry Biotechnology (Advances and Applications in Biotechnology)
This book explores recent advances on the use of microbes for agri-forestry biotechnological applications. It provides technical concepts and discussions on the use of microorganisms for processes such as bioprocessing, bioremediation, soil enhancement, aquaponics advances, and plant-host symbiosis. The book provides an overview of the microbial approach to the tools and processes used in agriculture and forestry that make or modify products, improve plants for specific uses, and make use of liv...
NMR Probeheads for Biophysical and Biomedical Experiments 2nd Edition is essential reading for anyone in the field of NMR or MRI, from students to medical or biological scientists performing experiments under certain physical and/or geometrical conditions, unattainable by conventional or available probes. The material guides the reader through the most basic and comprehensive stages in accomplishing a correct probe design, from a very basic oscillating circuit to much more elaborate designs.This...
Natural Products Isolation (Methods in Biotechnology, v. 20)
by Satyajit D Sarker, Zahid Latif, and Alexander Gray, Sir
This new edition of Natural Products Isolation has been not only significantly updated to reflect recent advances in the field, but has also been expanded with three new chapters on hyphenated techniques, purification by solvent extraction using partition coefficient, and isolation of microbial natural products. The book includes powerful cutting-edge techniques and simple basic techniques that can save time and effort, as well as achieve results equivalent to using some of the more modern and e...
Surface Modification of Biomaterials (Woodhead Publishing Series in Biomaterials)
The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material's surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of r...
Bioactive Materials in Medicine (Woodhead Publishing Series in Biomaterials, #33)
Bioactive materials in medicine provides readers with information on the current status and developments in bioactive materials for medical applications. Initial chapters focus on the fundamentals of bioactive of materials with chapters on such topics as nanotechnology and tissue engineering. Further chapters discuss laboratory design techniques with a view to clinical applications. The final few chapters review current biomedical applications such as drug delivery, gene therapy, plastic surgery...
Chloride Movements Across Cellular Membranes (Advances in Molecular & Cell Biology)
by Michael Pusch
All living cells are surrounded by a lipidic membrane that isolates them from the often harsh environment. However, to take up nutrients, to excrete waste, and to communicate among each other, Nature has invented an incredibly diverse set of transmembrane transport proteins. Specialized transporters exist to shuttle electrically charged ions, positive cations like sodium or negative anions like chloride, across the membrane. In the recent years, tremendous progress has been made in the field of...
Biomaterials In Asia: In Commemoration Of The 1st Asian Biomaterials Congress
This book is a compilation of the contributions by the outstanding scientists who attended the 1st Asian Biomaterials Congress. The 1st Asian Biomaterials Congress is the first integrated meeting on Asian biomaterials and was held in Tsukuba from 6 - 8 December 2007. The book showcases the latest and research developments in biomaterials and tissue engineering in Asia. It provides an overview of the recent advances of metallic, ceramic and polymeric materials, their composites, biomechanics, and...
Chemical Warfare Toxicology (Issues in Toxicology, 26-27)
Despite ongoing efforts to prohibit the production, storage and use of chemical warfare agents recent world events highlight the enduring threat to the population from these agents. Research efforts in various countries have resulted in novel insights into chemical warfare toxicology that has enabled the development of new approaches for the diagnosis and treatment of chemical warfare poisoning. This two-volume set provides an up-to-date treatise on the ongoing research into the toxicology of ch...
Multiple myeloma is a form of bone cancer. Specifically, it is a cancer of the plasma cells found in bone marrow (bone soft tissue). Normal plasma cells are an important part of the immune system. Mathematical models for multiple myeloma based on ordinary and partial differential equations (ODE/PDEs) are presented in this book, starting with a basic ODE model in Chapter 1, and concluding with a detailed ODE/PDE model in Chapter 4 that gives the spatiotemporal distribution of four dependent vari...
Metabolic systems engineering combines the tools and approaches of systems biology, synthetic biology, and evolutionary engineering. This book reviews studies on metabolism, from the earliest work of Lavoisier and Buchner to current cutting-edge research in metabolic systems engineering. This technology has been used in bioengineering applications to create high-performing microbes and plants that produce important chemicals, pharmaceuticals, crops, and other natural products. Current applicat...
Ultrafine Bubbles
Ultrafine bubbles (UFBs) are gas-filled bubbles with a diameter smaller than 1 μm. They are sometimes called bulk nanobubbles because these are not on a solid surface but inside a bulk liquid (water). They are already being used in commercial processes such as cleaning and plant cultivation. However, many mysteries still exist with respect to UFBs, such as mechanisms of stability, OH radical formation, and biological and medical effects. This is the first book on UFBs that reviews research done...
Mathematical Modeling of Complex Biological Systems (Modeling and Simulation in Science, Engineering and Technology)
by Abdelghani Bellouquid and Marcello Delitala
This book describes the evolution of several socio-biological systems using mathematical kinetic theory. Specifically, it deals with modeling and simulations of biological systems whose dynamics follow the rules of mechanics as well as rules governed by their own ability to organize movement and biological functions. It proposes a new biological model focused on the analysis of competition between cells of an aggressive host and cells of a corresponding immune system. Proposed models are related...
Over the past several decades there has been increasing research interest in thermodynamics as applied to biological systems. This concerns topics such as muscle work and internal energy such as fat and starch. Applications of the first and second laws of thermodynamics to the human body are important to dieticians and health science experts, and applications of these concepts to the animal body are a major concern of animal scientists. This book covers these key topics, which are typically not...
Written by a leading nanobiologist actively involved at the forefront of the field both as a researcher and an educator, this book takes the reader from the fundamentals of nanobiology to the most advanced applications. The book is written in such a way as to be accessible to biologists and chemists with no background in nanotechnology. It is reader-friendly and will appeal to a wide audience not only in academia but also in the industry and anyone interested in learning more about nanobiotechno...
Textbook of Ion Channels Volume I
The Textbook of Ion Channels is a set of three volumes providing a wide-ranging reference source on ion channels for students, instructors and researchers. Ion channels are membrane proteins that control the electrical properties of neurons and cardiac cells; mediate the detection and response to sensory stimuli like light, sound, odor, and taste; and regulate the response to physical stimuli like temperature and pressure. In non-excitable tissues, ion channels are instrumental for the regulatio...
Understanding Drug Release and Absorption Mechanisms
by Mario Grassi, Gabriele Grassi, Romano Lapasin, and Italo Colombo
Demand for better reliability from drug delivery systems has caused designers and researchers to move away from trial-and-error approaches and toward model-based methods of product development. Developing such models requires cross-disciplinary physical, mathematical, and physiological knowledge. Combining these areas under a single cover, Understanding Drug Release and Absorption Mechanisms builds a firm understanding ofall elements needed to conceive, build, and implement successful models of...
The question "Where do we come from?" has fascinated philosophers, scientists, and artists for generations. This book reorients the question of the matrix as a place where everything comes from (chora, womb, incubator) by recasting it in terms of acts of "matrixial/maternal hospitality" producing space and matter of and for the other. Irina Aristarkhova theorizes such hospitality with the potential to go beyond tolerance in understanding self/other relations. Building on and critically evaluatin...