The Poisoner's Handbook by Deborah Blum

The Poisoner's Handbook

by Deborah Blum

Equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is "a vicious, page-turning story that reads more like Raymond Chandler than Madame Curie." —The New York Observer

“The Poisoner’s Handbook breathes deadly life into the Roaring Twenties.” —Financial Times

“Reads like science fiction, complete with suspense, mystery and foolhardy guys in lab coats tipping test tubes of mysterious chemicals into their own mouths.”
 —NPR: What We're Reading

A fascinating Jazz Age tale of chemistry and detection, poison and murder, The Poisoner's Handbook is a page-turning account of a forgotten era. In early twentieth-century New York, poisons offered an easy path to the perfect crime. Science had no place in the Tammany Hall-controlled coroner's office, and corruption ran rampant. However, with the appointment of chief medical examiner Charles Norris in 1918, the poison game changed forever. Together with toxicologist Alexander Gettler, the duo set the justice system on fire with their trailblazing scientific detective work, triumphing over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice.

In 2014, PBS's AMERICAN EXPERIENCE released a film based on The Poisoner's Handbook.

Reviewed by MurderByDeath on

4.5 of 5 stars

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This is a fascinating look at the birth of forensic science in the United States from 1917 through the 1930's; specifically, at the revolutionary changes brought about by two men: the Chief Medical Examiner of New York City, Charles Norris, and toxicologist Alexander Gettler.  It's well-written, engrossing, and sometimes even sensational.   

The book is divided up by chapters, each representing one of the prevailing poisons of the jazz-age era and the crimes committed with them, with an inevitable focus on the effects of prohibition.  While there are some deviations within each chapter in order to maintain a chronology in the historical narrative, each chapter focusses on breaking down a specific poison, its physiological effects and methods of detection.  Blum does this in a way that is both accessible and fascinating...and sometimes gruesome.    

My only complaints are purely personal:  Blum wrote a thorough, comprehensive history of these two great men, but that requires a discussion of animal experiments, something I can't tolerate even as I recognise their contributions.  I also found that the emphasis on the dangers of prohibition-era alcohols grew tedious.  There's no way to write a history of this time frame without methyl- and ethyl- alcohols dominating the history, but I still found myself growing a bit weary of reading about them towards the end.   

What these two men accomplished in their time was phenomenal; their dedication, their perseverance is downright inspiring.  If you enjoy science and/or history, I'd recommend this book without reservation.

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Reading updates

  • Started reading
  • 3 May, 2016: Finished reading
  • 3 May, 2016: Reviewed