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Cowan’s Microbiology Fundamentals: A Clinical Approach is The Perfect Fit to align with your course. Here's why: The author team includes a practicing nurse to help students see how the content fits in their lives and relates to their future career on every page. A briefer text means all core concepts are covered, but streamlined to better fit the length of your course. A more modern, visual text and digital learning package fits with today’s students and the way they learn. Users who purchase C...

“RFK Jr. exposes the decades of lies.”—Luc Montagnier, Nobel laureateFrom the New York Times, Wall Street Journal, USA Today, Publishers Weekly bestselling author of The Real Anthony Fauci comes an explosive exposé of the cover-up behind the true origins of COVID-19. “Gain-of-function” experiments are often conducted to deliberately develop highly virulent, easily transmissible pathogens for the stated purpose of developing preemptive vaccines for animal viruses before they jump to humans. More...

Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retr...

This is the first book on ranaviruses. Ranaviruses are double-stranded DNA viruses that cause hemorrhagic disease in amphibians, reptiles, and fish. They have caused mass die-offs of ectothermic vertebrates in wild and captive populations around the globe. There is evidence that this pathogen is emerging and responsible for population declines in certain locations. Considering that amphibians and freshwater turtles are suitable hosts and the most imperiled vertebrate taxa in the world, ranavirus...

This detailed volume examines classical and cutting-edge methods involving double-stranded RNA (dsRNA), specifically regarding isolation, visualization, characterization, production, and application. Many protocols, such as co-immunoprecipitation-based isolation of double-stranded RNA-associated protein complexes, identification of mycoviruses by dsRNA extraction, application of dsRNA for fungi disease management (Sclerotinia sclerotiorum and Botrytis cin), and production of double-stranded RNA...

Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses an...

Viruses and RNAi share an intricate relationship at many levels. RNAi is an important antiviral defense mechanism in plants and invertebrates, microRNAs – of viral or cellular origin – affect many aspects of virus biology, and replication of many, if not all, mammalian viruses can be suppressed by RNAi. Antiviral RNAi: Concepts, Methods, and Applications provides a collection of protocols for the analysis of viral small RNAs and natural antiviral RNAi responses as well as for the development and...

There is currently increasing interest concerning the biology and disease caused by Acinetobacter species. Such interest, however, developed relatively slowly because of the necessity to clarify the confusing taxonomy of these organisms. Much work was needed to identify various species as members of this genus, to recognize their epidemiologic profile, their pathogenic role and their increasing importance as multi-antibiotic resistant organisms. In recent years improvement of genetic approaches,...

NEW YORK TIMES BESTSELLER • An urgent wake-up call about the future of emerging viruses and a gripping account of the doctors and scientists fighting to protect us, told through the story of the deadly 2013–2014 Ebola epidemic   “Crisis in the Red Zone reads like a thriller. That the story it tells is all true makes it all more terrifying.”—Elizabeth Kolbert, Pulitzer Prize–winning author of The Sixth Extinction   From the #1 bestselling author of The Hot Zone, now a National Geographic original...

Rabies: The Scientific Basis of the Disease and its Management, Fifth Edition is an authoritative reference on the current status of rabies, including the virological, clinical, and public health aspects of the disease. The Fifth Edition updates this classic reference with comprehensive coverage of the molecular virology, pathogenesis, diagnosis, immunology, treatment, epidemiology, and public health management of rabies. The book also covers One Health as it relates to rabies from concept to ap...

This volume explores computational methods for the rapid analysis of viral infections and strategies for their mitigation, which have significantly advanced the understanding of viral pathogenesis and host responses. Beginning with methods for identifying viral genomes from metagenomic sequencing data, the book progresses to topics such as next-generation sequencing to study host responses against viral infections, virus-host protein interactions to identify therapeutic targets, viral taxonomy,...

How a small number of risky experiments creates many unwieldy problems for life science research. The life sciences have never been more critical to human health, wealth, and security. But with any endeavor comes risk, and the last decade has seen concerns raised about gain-of function-research in which a microbe, usually a virus, is given new properties like enhanced lethality, transmissibility, or the capability to infect new species. In 2021 the term seeped into the tabloids when a conflict...

Big Pharma and health agencies cry "Don't take ivermectin!" A media storm follows. Why then, does the science say the opposite? Ivermectin is a dirty word in the media. The drug has been derided and declared useless. Doctors have earnestly recorded pleas asking those afflicted with COVID-19 not to take the drug. But why? The War on Ivermectin is the personal and professional narrative of Dr. Pierre Kory, the co-founder of an expert group of physicians', and his plight to alert the world of hi...