Vanadium Compounds (ACS Symposium S., #711)
Vanadium is now known to be one of the more biologically important transition elements. This volume focuses on vanadium chemistry and biochemistry and summarizes the role of vanadium in treating diabetes, concluding with a discussion of a human trial study. The volume looks in particular at model compounds that mimic the chemistry of nitrogenases as haloperoxidases. It also uncovers evolutionary aspects of haloperoxidases while examining structural and sequence relationships between these compou...
Validierung bioanalytischer Methoden (Essentials)
by Patric U B Vogel
In diesem Buch wird die Validierung bioanalytischer Methoden beschrieben. Bei der Qualitätskontrolle von biologischen Arzneimitteln kommen häufig bioanalytische Methoden zum Einsatz, um wichtige Eigenschaften wie den Gehalt oder mögliche Verunreinigungen zu überprüfen. Die eingesetzten Methoden müssen vertrauenswürdige Ergebnisse liefern, damit bei der Bewertung der Ergebnisse keine falschen Schlüsse gezogen werden. Die Vertrauenswürdigkeit wird durch eine Validierung sichergestellt. Die Validie...
Gel Permeation and Ion-Exchange Chromatography of Proteins and Peptides
This book is a collection of critical reviews of the use of high-performance liquid chromatography in a very specialized area of research. It describes in detail modern methodology to separate nucleic acids, enzymes and a wide variety of biologically active proteins such as renin.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingeschichtliche Forschung zur Verfügung, die jeweils im historischen Kontext betrachtet werden müssen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.
There have been important developments in the last decade: computers are faster and more powerful, code features are enhanced and more efficient, and larger molecules can be studied — not only in vacuum but also in a solvent or in crystal. Researchers are using new techniques to study larger systems and obtain more accurate results. This is impetus for the development of more efficient methods based on the first-principle multi-level simulations appropriate for complex species.Among the cutting-...
Computers have become an integral part of chemistry. Virtually all modern scientific instrumentation contains some form of computer and, indeed, the operation of many instruments has become so complex that it is impossible without some degree of computer control. It is vital for the modern student of chemistry to have at least a basic knowledge of computers, and the deeper that knowledge is, the better use will be made of the techniques available. Computers in Chemistry provides an excellent o...
Analytical Gas Chromatography
by Walter Jennings, Eric Mittlefehldt, and Phillip Stremple
Gas chromatography remains the world's most widely used analytical technique, yet the expertise of a large proportion of chromatographers lies in other fields. Many users have little real knowledge of the variablesin the chromatographic process, the interaction between those variables, how they are best controlled, how the quality of their analytical results could be improved, and how analysis times can be shortened to facilitate the generation of a greater numberof more reliable results on the...
CRC Handbook of Nucleobase Complexes (CRC Press Revivals)
by James R. Lusty
The purpose of this easy-to-use handbook is to provide a quick, accessible reference to nucleobase complexes. It describes these complexes with reference to methods of preparation, their characterization, and their toxicity and therapeutic indices. It lists the modes of coordination together with the relevant spectral data and major methods of investigation. This concise resource guide also includes data on the uncomplexed bases, such as solubility, pk, accepted structures in the solid state and...
Stereochemie - Grundbegriffe richtet sich an Studenten, Lehrende und praktizierende Wissenschaftler der Chemie, Biochemie, Pharmazie, Medizin und Biologie, die sich mit dem Ph??nomen der Chiralit??t befassen. Neben einer genauen Formeldarstellung ist eine klare und eindeutige Terminologie zur Beschreibung der dreidimensionalen Strukturen und der daraus resultierenden Konsequenzen f??r Reaktionen oder Wirkstoff-Rezeptor-Wechselwirkungen unerl????lich. Das gilt umsomehr im zunehmenden interdiszipl...
In this humane and important exploration of modern medicine, Druin Burch examines the future of medicine, our changing physicalities and the implications of longer life. From birth to death and through the exploration of topics such as disease, sex, mind, eating and drinking, Burch tracks the future of medicine by looking at what is already possible today. Weaving in insights from literature, art and history, The Shape of Things to Come considers the cultural complexity surrounding medicine as w...
This book is intended for graduate students and researchers working in fields related to mass spectrometry. It covers the basic principles of key components of various types of mass spectrometry, recent developments and applications in different fields including material analysis, pollutant measurements for environmental applications, biomedical applications, disease diagnosis and drug developments.
Frontiers in Clinical Drug Research-Hematolog (Frontiers in Clinical Drug Research - Hematology, #5)
by Atta-ur Rahman
This book provides the reader with an illustrative overview concerning successful and widely used applications of organocatalysis in the field of natural product synthesis. The main focus will be on organocatalytic key-steps for each (multi-step) synthesis described, whereas other often particularly innovative transformations will be omitted, as this would be beyond the scope of this volume.
In this fifth edition of Jack Jie Li's seminal "Name Reactions", the author has added twenty-seven new name reactions to reflect the recent advances in organic chemistry. As in previous editions, each reaction is delineated by its detailed step-by-step, electron-pushing mechanism and supplemented with the original and the latest references, especially from review articles. Now with addition of many synthetic applications, this book is not only an indispensable resource for advanced undergraduate...
Intended specifically for practicing professionals and advanced students in chemistry and biochemistry, this invaluable book covers the full range of the computer applications in these fields, including numerical, nonnumerical, and graphics applications. New material includes multiple linear regression using MREG, principal-components analysis, Monte Carlo integration, parameterization of the force field, and molecular modeling software. Major areas covered include: * Error, Statistics, and...
Laboratory Experiments for Chemistry and the Living Organism
by Molly M. Bloomfield and Joseph M. Bauer
Features a conversational writing style and includes special emphasis on applications from the health sciences. Motivates the study of chemistry by showing how each of the chemical concepts is important in the student's own life. Includes worked-out examples, in-chapter exercises, a comprehensive glossary and optional topics for more advanced students.
New-Generation Bioinorganic Complexes
Bio-Inorganic compounds are successfully applied as therapeutic agents since decades. Thus, scientist designed new metal complexes bearing biomolecules as ligands, investigating their potential as bioactive and therapeutic agents. This book presents a comprehensive overview on materials design, substance classes and their characterization. This book is compiled for scientists interested in medical application of bioinspired materials.
Textbook of Biochemistry with Clinical Correlations
This book presents a clear and precise discussion of the biochemistry of eukaryotic cells, particularly those of mammalian tissues, relates biochemical events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of abnormal biochemical processes in human disease. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to human diseases.
Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives (Springer Theses)
by Tsukasa Mizuhara
The author successfully developed novel anti-HIV PD 404182 derivatives that exhibited submicromolar inhibitory activity against both HIV-1 and HIV-2. His thesis is in three parts. The first part expounds efficient methods for the synthesis of tricyclic heterocycles related to PD 404182 based on the sp2-carbon−heteroatom bond formations. Starting from arene or haloarene, C-O, C-N, or C-S bonds were formed by simply changing the reactants. These synthetic methods provide powerful approaches for th...
Biochemical studies on some sera aLkaline Phosphatase isoenzymes HALP, HSALP in Breast cancer
by Samea Ibrahim Alkarkhi-, Nazar Naji Altikriti, and Sami a Al-Mudhaffar Dr
Polymers in Nanomedicine (Advances in Polymer Science, #247)
Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery, by Ernst Wagner Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine, by Takami Akagi, Masanori Baba and Mitsuru Akashi Biodegradable Polymeric Assemblies for Biomedical Materials, by Yuichi Ohya, Akihiro Takahashi and Koji Nagahama PEGylation Technology in Nanomedicine, by Yutaka Ikeda and Yukio Nagasaki Cytocompatible Hydrogel Composed of Phosphol...