B Chromosomes in the Eukaryote Genome
B chromosomes are additional passengers found in the karyotypes of about 15% of eukaryote species. They are best understood as genome parasites exploiting the host genome because of their transmissional advantage, and are frequently deleterious for the organism carrying them. Since the last compilation of B chromosome literature more than 20 years ago, many new findings have contributed to building an increasing body of knowledge of these mysterious genetic elements. This single topic issue of C...
Humangenetische Diagnostik (Ethics of Science and Technology Assessment, #7)
by C R Bartram, J. P. Beckmann, F Breyer, G Fey, C Fonatsch, B Irrgang, J Taupitz, K -M Seel, and F Thiele
Durch die Human-Genomforschung bieten sich faszinierende Moeglichkeiten fur die Pravention, Diagnose und Therapie von Krankheiten. Allerdings sind mit dieser Forschung - insbesondere mit der Anwendung der gewonnenen Ergebnisse in der medizinischen Praxis - auch Risiken verbunden. Vielfach gibt es fur den Umgang mit diesen Risiken und den damit verbundenen Entscheidungsunsicherheiten noch keine gesellschaftlich akzeptierten Prozeduren. Besonders die Anwendung genetischer Tests im Gesundheitsberei...
This book constitutes the post-proceedings of the DIMACS/RECOMB Satellite Workshop on Computational Methods for SNPs and Haplotype Inference held in Piscataway, NJ, USA, in November 2002. The book presents ten revised full papers as well as abstracts of the remaining workshop papers. All relevant current issues in computational methods for SNP and haplotype analysis and their applications to disease associations are addressed.
In Germs, Genes and Civilization, Dr. David Clark tells the story of the microbe-driven epidemics that have repeatedly molded our human destinies. You'll discover how your genes have been shaped through millennia spent battling against infectious diseases. You'll learn how epidemics have transformed human history, over and over again, from ancient Egypt to Mexico, the Romans to Attila the Hun. You'll learn how the Black Death epidemic ended the Middle Ages, making possible the Renaissance, weste...
Biotechnology and Genetic Engineering Reviews
Methods enabling the direct study of genetic variation in natural populations have improved considerably. The new edition explores these updated techniques in DNA analysis and provides a revised and refined laboratory guide to investigating variation in DNA molecules.
Distinguished evolutionary geneticist John Avise reviews recent discoveries in molecular biology, evolutionary genetics, and human genetic engineering, and explains how they relate to our development—not just our metabolism and physiology, but also our emotional disposition, personality, ethical leanings, and, indeed, religiosity.
Current research in genomics and pharmacogenomics is increasingly highlighting the need to move towards stratified disease descriptions and individualized treatment plans. This book explains how a confluence of recent biological, technological and methodological developments is making it possible to provide personalized diagnoses and treatments.By virtue of treating each person's condition as unique, personal genomics and personalized medicine require health professionals to understand the natur...
Traite Philosophique Et Physiologique de l'Hérédité Naturelle Dans Les États de Santé Et de Maladie Du Système Nerveux, Vol. 2
by Prosper Lucas
Who were the early ancestors of East European Ashkenazic Jews, when and from where did they arrive in Eastern Europe, and how were they related to the biblical Israelites/Judeans? This book intends to answer these questions, but first it discusses the switch from a patrilineal system (Israelites/Judeans) to a matrilineal one including converts (Jews), and the switch from ashkenazim by descent to ashkenazim by rites, important topics not mentioned in the literature pertaining to the current subje...
This book emerged from a series of lectures on crop evolution at the Faculty of Agriculture of The Hebrew University of Jerusalem. While many textbooks are available on general evolution, only a few deal with evolution under domestication. This book is a modest attempt to bridge this gap. It was written for advanced undergraduate and graduate students in the fields of crop evolution, ethnobotany, plant breeding and related subjects. Evolution under domestication is unique in the general field of...
Computational Biology of Non-Coding RNA (Methods in Molecular Biology, #1912)
This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene...
Twin and Family Studies of Epigenetics (Translational Epigenetics)
Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, tw...
Riboswitches (Methods in Molecular Biology, #540)
The transfer of hereditary information from genes to proteins is one of the essential pr- esses in all living organisms on our planet. Some genes are expressed without modu- tion throughout the life of a cell, while many others require various degrees of control to precisely balance cellular metabolism with environmental conditions. For many years, researchers attributed this regulatory function to protein molecules, which can direct gene expression at multiple levels, in response to various inp...
Heat Shock and Other Stress Response Systems of Plants
In the course of evolution, plants have acquired a whole set of distinct but partially overlapping stress response systems helping them to survive and propagate under a multitude of unfavourable environmental conditions. The book deals mainly with the molecular and cell biological aspects of stress response. A concise description of heat shock is followed by a discussion of similarities and differences with regard to other stress response systems. These include oxidation, heavy metals, anaerobio...
Eukaryotic Chromosomes
Theoretical and practical aspects of cytogenetics are both approached by well-known scientists. A detailed presentation of the structure and function of eukaryotic chromosomes gives a comprehensive overview of this modern field.
Der Band bietet eine umfassende und prazise Darstellung der klassischen wie der modernen Genetik: Entwicklungsbiologie und genetik, Humangenetik, Neuro- und Verhaltensgenetik sowie Chromosomenforschung. Fur die 5. Auflage wurde das Lehrbuch grundlegend uberarbeitet und aktualisiert. Es beinhaltet das Grundlagenwissen der Genetik fur das gesamte Studium. Die Inhalte werden durch zahlreiche Lernhilfen und Beispiele aus allen Bereichen der Genetik vermittelt. Alle Abbildungen sind im Internet frei...
Provides outlines for learning about genetics through having actual experiences.
This textbook on genetics provides students with coverage of molecular genetics. Using easy-to-follow language, the book covers transmission, molecular and population genetics, as well as developmental genetics, gene cloning and manipulation, and genes and cancer.
"Principles of Genetics, 7/e" offers an up-to-date, balanced treatment of the major areas of genetics (classical, molecular, and population genetics) in a friendly writing style with excellent learning aids, making it easier for students to learn and succeed.
Principles of Gene Manipulation (Studies in Microbiology)
As in past editions, the basic philosophy of this extremely popular text remains to present the principles and techniques of gene manipulation in sufficient detail to enable the non-specialist reader to understand them. However, in the three years since the previous edition, molecular biology has seen a dramatic increase in available techniques and applications. Every chapter in this new edition has been extensively revised or rewritten to take these developments into account - including a vastl...
Plant Cytogenetics
Plants have played a significant role in the discovery of inheritance principles and many biological phenomena, such as the chromosomal basis of inheritance, the genome dynamics conferred by transposable elements, or the evolutionary implications of chromosomal mutations. While the molecular basis of gene structure and function has been widely studied, many aspects of chromosome structure, its functional significance and evolutionary implications remain to be established. This special issue of...