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This work focuses primarily on identifying the research needs in this area of neurotoxicology. Based on papers presented for the International Symposium on Aluminium Toxicity, held in Vancouver in 1995, it reviews the knowledge and research required in each specific area.

Marine Mammal Ecotoxicology: Impacts of Multiple Stressors on Population Health provides tactics on how to develop a comprehensive methodology for the study of existing threats to marine mammals. By presenting a conservation-biology approach and new and emerging technologies, this work helps provide crucial knowledge on the status of marine mammal populations that not only helps readers understand the ecosystem’s health, but also instigate mitigation measures. This volume provides information th...

Mutagenicity: Assays and Applications presents an extensive examination of the detection, assessment and future of mutagenicity, particularly as it concerns human health and the environment. Chapters focused on specific types of mutagens or testing methods for their detection collectively explore the current state of human and environmental mutagenesis, future perspectives and regulatory needs. The test procedures for measuring mutagenicity, their advantages and limitations are described with pr...

This text provides a short review of venoms used by animals to defend themselves or to capture prey. Venomous or poisonous animals are widely distributed throughout the animal kingdom, with birds appearing to be the only large and widespread group in which no venomous species has been discovered. By research in this field scientists have learned, and will learn, much about animal behaviour and physiology. The active venom components, the toxins, have proved to useful tools for studying human phy...

A decade after publication of the first edition, Handbook of Venoms and Toxins of Reptiles responds to extensive changes in the field of toxinology to endure as the most comprehensive review of reptile venoms on the market. The six sections of this new edition, which has nearly doubled in size, complement the original handbook by presenting current information from many of the leading researchers and physicians in toxinology, with topics ranging from functional morphology, evolution and ecology...

Genetic toxicology is considered to be an important assessment tool as there is genetic impact of artificial chemicals. Insight on Genotoxicity discusses testing, mechanism, prediction, and bioindicator of genotoxicity taking into consideration recent advances in nano-engineered particles. Corollary of DNA dent is also discussed in detail taking into consideration the impact of ICH guidelines on genotoxicity testing, which is important for drug discovery innovation and development. Perspective r...

This volume focuses on exposure assessment for occupational hygiene purposes, such as compliance and control measures, as well as for application in occupational epidemiology. Key concepts and methods of exposure modelling are addressed and the wide applicability of these strategies is illustrated in various areas (compliance testing, quantification of local sources of exposure, and exposure assessment in epidemiologic surveys). The book should be of interest to graduates of occupational hygiene...

Already regarded as a standard reference for anyone who needs to know about the actions and uses of anti-inflammatory and analgesic drugs, this second edition provides even more. It updates information on the medicinal chemistry and the pharmaceutics of ibuprofen and its pharmacokinetics in both humans and animals. It includes molecular pharmacology and toxicological studies, and discusses the safety and efficacy of non-prescription ibuprofen, including its side effects. The text also addresses...

With laboratory animals, especially rabbits, playing such an important role in biomedical research, the humane care of these animals is an ongoing concern. The Laboratory Rabbit, Second Edition presents basic information and common procedures in detail to provide a quick reference for caretakers, technicians, and researchers in a laboratory setting. Now in full color, the second edition of this book illustrates management practices and technical procedures with numerous figures and tables. It i...

Introduction to In Vitro Cytotoxicology examines in vitro cytotoxicology, which offers new methodologies to toxicity testing. This important new discipline of modern toxicology is gaining increased acceptance as a viable alternative to traditional testing methods. The text discusses the application of in vitro cytotoxicology to toxicity testing and human risk assessment, and it analyzes the advantages and limitations of the tests performed under scientific and regulatory conditions. The book als...

Capturing the growth of the global medical device market in recent years, this practical new guide is essential for all who are responsible for ensuring safety in the use and manufacture of medical devices. It has been extensively updated to reflect significant advances, incorporating combination products and helpful case examples of current real-life problems in the field. The Third Edition explores these key current trends: global device marketscontinually advancing technologythe increasing h...

The use of chemicals in any workplace in the developed world is governed by stringent health, safety and environmental legislation, and companies spend significant amounts of time and money assessing the risks associated with the handling and use of chemicals. In practice, those risk assessments are generally carried out by a range of competent people, be it the corporate safety manager, the R&D chemist or the manufacturing unit manager. This book will guide those personnel in the understanding,...

Brainstorming Questions in Toxicology is designed to serve as a comprehensive, quick reference supplement for various examinations that include sections on toxicology. It reflects the breadth and multidisciplinary nature of toxicology with an objective approach to the subject. With 3500 short questions and answers, multiple choice questions, true/false or correct/incorrect statements, fill in the blanks, and matching the statements, this book is a helpful tool for students, teachers and toxicolo...

Key featuresContains 28 updated tables designed as quick, easy-to-use references for New and Old World speciesProvides over 100 photographs and illustrations, most now in color, depicting aspects of nonhuman primate biology, behavior, management practices, diseases, and technical proceduresGives a concise overview of regulatory considerations for the use of nonhuman primates in biomedical researchExpands the Veterinary Care chapter to include new sections on nutritional support, behavioral condi...

Persistent organic pollutants (POPs) and toxic elements, such as dioxins, flame retardants, lead and mercury, are substances of major concern for the food industry, the regulator and the public. They persist in the environment, accumulate in food chains and may adversely affect human health if ingested over certain levels or with prolonged exposure. Persistent organic pollutants and toxic metals in foods explores the scientific and regulatory challenges of ensuring that our food is safe to eat....

This fully revised edition of the practical classic on health hazards for artists is available yet again, with all pertinent information on safety and labeling and new chemicals brought absolutely up to date. It clearly highlights the potential dangers for artists in such fields as painting, photography, ceramics, sculpture, printmaking, woodworking, textiles, and many others. It also has an important - and newly revised - section on health hazards for children working with art materials. And Dr...

First published in 1988, many chemical compounds present in workplace settings can produce a number of impairments in the human nervous system. As the situations in which neurotoxic agents have been recognized in exposed workers has grown, so has the importance of occupational neurotoxicology as a specialty. Addressing some of the most vital concerns in the field, Occupational Neurotoxicology discusses: Neurotoxic agents commonly encountered in the workplace Signs and symptoms of neurotoxicity...