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Eine grosse Anzahl heterocyclischer Naturstoffe leitet sich vom Ring- system des Piperidins (1) ab. Als Substituenten einfach oder mehrfach substituierter Piperidinbasen finden sich Methyl-, Carboxyl-, Hydroxyl- und Aminogruppen sowie aliphatische Seitenketten unterschiedlicher Lange. Die Substitution erfolgt bevorzugt an den C-Atomen 2, 3 und 6 sowie am Heteroatom. In zahlreichen Fallen ist der Piperidinring in a- oder ss-Stellung direkt oder uber eine C-Brucke mit einem weiteren Heterocyclus v...

Saponins are complex molecules made up of sugars linked to a triterpenoid or a steroid or a steroidal alkaloid. These natural products are attracting much attention in recent years because of the host of biological activities they exhibit. The diversity of structural features, the challenges of isolation because of their occurrence as complex mixtures, the pharmacological and biological activities still to be discovered, and the prospect of commercialization - these all are driving the study of...

The modern biosciences make many new proteins available. Nevertheless the handling of these proteins is quite difficult due to problems with their stability. This collection gives - in the form of tables - protein stability data for various temperatures and solvents. These data are most useful for the development of protein folding and the improvement of biotechnological stability for applications of proteins. The first supplement contains material covering 1997-1999. Some previous data have als...

Many of the reactions and compounds involved in metabolism are almost iden tical in the different groups of living organisms. They are known as primary me tabolic reactions and primary metabolic products. In addition, however, a wide variety of biochemical pathways are characteristic of only a few species of organ isms, of single "chemical races," or even of a certain stage of differentiation of specialized cells. Such pathways are collectively referred to as "secondary metab olism," and the com...

The discovery of novel drugs that fill unmet medical needs is important for the health and well-being of people everywhere. However, the general public knows too little about the pathways through which basic research discoveries are translated into products that protect or restore human health. In the second edition of Hallelujah Moments, Eugene H. Cordes reveals the processes and pitfalls on the route from the laboratory bench to the bedside. These are adventure stories in which wit and grit cr...

Natural Products in the Chemical Industry is not a conventional textbook, but rather an invitation to join an entertaining journey that takes you into the fascinating world of natural products. This book features diverse compound classes from a number of areas: colour­ants, fragrances and flavourings, amino acids, pharmaceuticals, hormones, vitamins and agrochemicals. Whether you are a teacher or a scholar, an undergraduate or gradu­ate student, a professional chemist in industry or academia, or...

The second edition of this book has drawn heavily on the first edition but a huge amount of research on steroid analysis has been published over the last 15 years. As a result, the Editors decided to let the first edition of this book stand on its own and direct readers interested in pre-1995 steroid analysis to it, simply because the post-1995 research can on its own fill the second edition. We have tried to keep a balance but equally have allowed authors of each chapter a significant degree of...

The first and only guide to showcase the impact of phage display technology on drug discovery, this reference details the theories, principles, and methods impacting the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. Highlighting the current and future role of phage display in the development of protein therapeutics, this book provides a comprehensive overview that will prove invaluable to anyone researching recombin...

The Internet can provide several cost-saving alternatives for the purchase of prescription drugs. Without adequate information, however, it can also be a dangerous alternative. Buying Rx Drugs Online serves as a smart consumer guide for anyone who is considering going online for medications. It covers the full range of the online pharmaceutical experience, explaining both the benefits and the dangers, as well as why medical professionals should be kept in the loop. It examines the convenience an...

The book covers theoretical background and methodology as well as all current applications of Quantitative Structure-Activity Relationships (QSAR). Written by an international group of recognized researchers, this edited volume discusses applications of QSAR in multiple disciplines such as chemistry, pharmacy, environmental and agricultural sciences addressing data gaps and modern regulatory requirements. Additionally, the applications of QSAR in food science and nanoscience have been included -...

This book focuses on different techniques of asymmetric synthesis of important compounds, such as drugs and natural products. It gives insightful information on recent asymmetric synthesis by Inorganic, Organic and Enzymatic combinations. It also emphasizes chiral compounds and design of new catalyst for synthesis of compounds.

An important resource for the synthesis of intermediates of specialty chemicals, pharmaceuticals and fine chemicals. Aromatic Hydroxyketones from Butanone to Dotriacontanone provides the reader with exhaustive information covering structure, preparation, physicochemical characteristics, as well as a related bibliography. The handbook is presented in dictionary style, with a logical classification of the ketones, making the information easily available for consultation. The book is aimed at those...