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Chitin and chitosan are key materials in the 21st century. They have multifunctional properties with applications in the pharmaceutical sciences, environmental problem-solving (such as water-cleaning), fibres, films and hydrogels, in cosmetics, food additives and as agricultural materials. For this book the most active authors in the field summarize the basics and applications of chitin and chitosan, keeping in mind their importance in contemporary science and technology.

Winner of the 2018 Gold National Health Information Award and 2018 APEX Merit Award! NBC Today show nutrition and diet guru Madelyn Fernstrom and award-winning neuroscientist and pharmacologist John Fernstrom —partnering with AARP— present the ultimate guide to food and medicine interaction. Millions of Americans take prescription drugs to treat diabetes, high blood pressure, heart disease, or other conditions. But beware: The foods you eat and the medications you take could be working against...

Since ocular therapeutics and drug delivery is a subject of interest to specialists from various disciplines such as chemical, biochemical, medical, pharmaceutical, and toxicological, it truly presents a unique situation requiring a multi-disciplinary approach in understanding and addressing various problems. Yet we see that scientists associated with these areas are working, by and large, independently of one another, thus limiting dissemination of knowledge, experience and ideas that would gre...

Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery technologies that utilize both systemic and local routes of administration, Targeted Delivery of Small and Macromolecular Drugs brings together field experts who summarize current progress and discuss...

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling an...

Learn the public health implications of shifting drug-related risks among the inner city poorInner city drug use behavior shifts and changes, leaving past drug treatment programs, drug prevention efforts, health care provisions for drug users, and social service practice unprepared to effectively respond. New Drugs on the Street: Changing Inner City Patterns of Illicit Consumption tackles this problem by presenting the latest ethnographic and epidemiological studies of emerging and changing drug...

The chemistry of condensed tannins has hitherto represented a relatively unattractive and therefore neglected area of study; one in which the weight of research effort involved is invariably disproportionate to the results achieved, in which the participating schools generally confine their approach to specific molecular species, and in which as yet no consensus has been reached regarding likely precursors. The problems which beset those engaged in this field represent a combined function of the...

This volume is part of a series, inaugurated in 1938, now referred to simply as "Zechmeister" after its founder, L. Zechmeister. It contains contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a reconized authority in his field, and provides a comprehensive and up-to-date review of the topic in quest...

Substances belonging to this group of organic compounds are wi,lely distributed in Nature, being found in plants, both higher and lower fungi and, upto the present time, in one animal source, sheep wool-fat. For a long­ time no real differentiation was possible between the tetra- and penta­ cyclic triterpenes and the sterols. Then the two latter became disting­ uishable by their selenium. ·dehydrogenation products, i. e. , picene and naphthalene derivatives from the pentacyclic triterpenes and D...

An exploration of high-throughput synthesis, this book presents a compilation of how-to methods, novel materials, and catalyst developments for creating a multitude of new compounds. Introductory sections are coupled with in-depth case studies clarifying theory through practice. The book emphasizes the potential for reproducing experiments in detail.

Das vierbändige Standardwerk für die grundlegende praktische Arbeit im chemisch-pharmazeutischen Labor mit Schwerpunkt Synthesemethoden, Chromatographie und Spektroskopie liegt jetzt in der 6. völlig neu überarbeiteten Auflage vor. Es dient Berufseinsteigern als breit angelegtes Lehrmittel und erfahrenen Fachkräften als Nachschlagewerk mit übersichtlich dargestellten theoretischen Grundlagen und konkreten, erprobten Anwendungsideen. Die theoretischen Grundlagen für jedes Kapitel sind gut lesba...

This title is a comprehensive text that addresses key aspects of nanomedicine such as properties occurring at the nanoscale that have unique medical effects, great molecular knowledge of the human body and disease processes, and apparent clinical translation as opposed to narrow insufficient texts that address only a few topics and attempt to “rebrand” established drug delivery. It will clearly define the field which is needed due to the immaturity and broad nature of the field. The book is alig...

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and...

A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confoca...

For undergraduate-level courses in Chemistry, Biology, Sociology, Criminal Justice and Health and Drug Education. Drugs and the Human Body, 7th Edition, addresses the effects of high-use, high-abuse drugs in America in a timely and straightforward fashion. It reflects the most recent research on the most highly addictive drugs, including street, over-the-counter, and prescriptive drugs. It is designed to be easily accesible to the non-science major, yet comprehensive enough for use by the pract...

Unlike Western medicine that's generally packaged in antiseptic whiteness with frightening symbols to beware, Chinese pharmaceuticals look lively, exotic and certainly tasteful. Simon Go, author and a lover of Chinese medical packaging, spent years visiting manufacturers and medical stalls/pharmacy shops looking for these wonderful packages and begging shopkeepers to go through their backrooms in search of old unused medicines. Hong Kong Apothecary is divided into medicinal sections (infusion oi...

​Das Buch gibt eine Anleitung zur Beschreibung von Säure-Base-Gleichgewichten mithilfe von einfach zu konstruierenden Diagrammen, die es erlauben, - pH-Werte von Lösungen grafisch zu ermitteln, - Gleichungen für die Berechnung von pH-Werten abzuleiten (die möglichen Näherungen zu erkennen), - den Verlauf von Titrationskurven einfach auf grafischem Weg zu ermitteln, - die in Säure-Base-Systemen bei bestimmten pH-Werten dominierenden Spezies zu erkennen, usw. Das Buch ist insbesondere für Stu...

In dem vorliegenden Buch, das anläßlich des Symposiums "Atherogenität der Triglyceride" im Mai 1991 auf Schloß Fuschl entstand, werden alle Aspekte der Epidemiologie, Diagnostik und Therapie bei erhöhten Triglyceridwerten zu­ sammengefaßt. Eine Erhöhung der Triglyceridspiegel im Rahmen einer Fettstoffwechsel­ störung wird häufig in Verbindung mit anderen Erkrankungen, wie Hypertonie und Diabetes, beobachtet. Aus diesem Grund ist die Atherogenität für die Patienten von besonderer Bedeutung. Das B...

As a result of new statistical and mathematical approaches, improved visualization tools, and recognition by international regulatory groups, quantitative structure-activity relationships (QSARs) now play important roles in pharmacology for the design of new drugs as well as in toxicology and ecotoxicology for hazard identification and risk assessment. Providing up-to-date coverage of the field, Three Dimensional QSAR: Applications in Pharmacology and Toxicology presents the most recent QSAR met...

Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo

A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneou

With the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease. Gene-profiling technologies and the concept of individualized medicine are leading to the development of drugs with enhanced specificity. This promises to lead to more effective treatment of diseases with reduced risk of side effects. Gene Profiling in Drug Design provides insights fr...