Aerosol Pollution Impact on Precipitation
Life on Earth is critically dependent upon the continuous cycling of water between oceans, continents and the atmosphere. Precipitation (including rain, snow, and hail) is the primary mechanism for transporting water from the atmosphere back to the Earth’s surface. It is also the key physical process that links aspects of climate, weather, and the global hydrological cycle. Changes in precipitation regimes and the frequency of extreme weather events, such as floods, droughts, severe ice/snow sto...
The modern biosciences make many new proteins available. Nevertheless the handling of these proteins is quite difficult due to problems with their stability. This collection gives - in the form of tables - protein stability data for various temperatures and solvents. These data are most useful for the development of protein folding and the improvement of biotechnological stability for applications of proteins. The first supplement contains material covering 1997-1999. Some previous data have als...
Pharmacogenomics (Drugs and the Pharmaceutical Sciences)
"Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."
Moderne Naturstoffchemie am Beispiel Des Pilzgiftstoffes Philloidin
by Theodor Wieland
Functional Hydrogels in Drug Delivery
The book deals with the synthesis and characterization of hydrogels specifically used as drug delivery systems. Each chapter includes the most recent updates about the different starting materials employed and the improvement of their physicochemical and biological properties to synthetize high performing carriers for specific uses.
Process Development (Oxford Chemistry Primers, #30)
by Stan Lee and Graham Robinson
Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. In this concise text the authors use real examples to show the problems which may be encountered in scaling up chemical syntheses and the ways in which these problems may be overcome. The major part of the book is devoted to genuine case histories from ICI/Zeneca Pharmaceuticals. Through a range of carefully chosen examples, the book explains how it is...
Nanobiotechnology is one of the key technologies of the 21st century. Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies including their preparation methods, evaluation of their safety and efficiency, and their interaction with biologicals and application in biotechnology.
Sulfonium compounds have been known to the organic chemist for almost 90 years. During most of this period they remained curiosities, well suited for didactic purposes to illustrate certain similarities to ether adducts and to organic ammonium compounds. Their exploration remained largely in the academic realm, because no unusual practical applications were found in spite of a steady increase in the attention paid to them. An event that occasionally puts a class of compounds into the center of i...
Engineered Nanoparticles as Drug Delivery Systems (Emerging Materials and Technologies)
by Nahid Rehman and Anjana Pandey
This book highlights application of nanomaterials for drug delivery, therapy, and engineering. It covers stimuli-sensitive drug delivery systems including an overview of the physical, chemical, biological, and multi-stimuli responsive nano systems. It also presents analysis of clinical status for different types of nano platforms and assesses novel applications of nanomaterials in the areas of smart delivery and drug targeting. It further discusses the advantages and disadvantages of each applic...
Modified-Release Drug Delivery Technology, Second Edition (Drugs and the Pharmaceutical Sciences)
by Michael J Rathbone
This two volume Second Edition describes the anatomical, physiological, pharmaceutical, and technological aspects of oral, colonic and rectal, ocular, oral mucosal, dermal and transdermal, nasal, vaginal, and pulmonary delivery routes, providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value. Topics include:
Micro- and Nanotechnologies-Based Product Development
Covers micro- and Nano- technologies approaches with current trends with safety and efficacy in product development. Presents overview of recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements. Provides comprehensive overview of latest research related to the micro and nanotechnological including designing, optimization, validation, scale of micro and nanotechnologies. This book is edited by the two-well known researc...
Parenteral Medications, Fourth Edition
Parenteral Medications is an authoritative, comprehensive reference work on the formulation and manufacturing of parenteral dosage forms, effectively balancing theoretical considerations with practical aspects of their development. Previously published as a three-volume set, all volumes have been combined into one comprehensive publication that addresses the plethora of changes in the science and considerable advances in the technology associated with these products and routes of administration....
Hardbound. Impurity profiling is the common name of a group of analytical activities, the aim of which is the detection, identification/structure elucidation and quantitative determination of organic and inorganic impurities, as well as residual solvents in bulk drugs and pharmaceutical formulations. Since this is the best way to characterise the quality and stability of bulk drugs and pharmaceutical formulations, this is the core activity in modern drug analysis.Due to the very rapid developmen...
Appropriate Dose Selection - How to Optimize Clinical Drug Development (Ernst Schering Foundation Symposium Proceedings, #59)
Optimal dose individualization has become more important in improving clinical efficacy and safety. This is due in part to the variability in drug response. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. This book reviews innovative methods, tools and examples of rational drug development strategies, particularly for novel oncological agents.
Modern Magnetic Resonance
A comprehensive collection of the applications of Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI) and Electron-Spin Resonance (ESR). Covers the wide ranging disciplines in which these techniques are used:* Chemistry;* Biological Sciences;* Pharmaceutical Sciences;* Medical uses;* Marine Science;* Materials Science;* Food Science. Illustrates many techniques through the applications described, e.g.:* High resolution solid and liquid state NMR;* Low resolution NMR, especially im...