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Antimicrobial-biocidal products are topical antiseptics, most commonly formulated with the idea of exploiting potential synergies resulting from the combined substances in these mixtures. There are many ways of looking for and defining synergy within this important scientific field, which has resulted in some confusion and controversy among researchers. This book brings the myriad of concepts and methods together in one volume to clarify the science for the pharmaceutical industry. It includes i...

The Shulgin Index is a comprehensive collection of the known psychedelic phenethylamines and related compounds. There are 126 main compounds with detailed physical properties, synthesis and analytical chemistry, biochemistry, pharmacological properties, and legal status. Fully referenced with over 2,000 citations. There are sub-tables of lesser-studied structural homologues and analogues, over 1300 total compounds covered. GCMS scans are included for 229 compounds. This book is an invaluable res...

Written in such a way as to make it accessible to toxicologists who do not have English as a first language, this book focuses on evaluating, interpreting and reporting results of regulatory toxicology studies.

The long awaited second edition of Principles and Practice of Pharmaceutical Medicine provides an invaluable guide to all areas of drug development and medical aspects of marketing. The title has been extensively revised and expanded to include the latest regulatory and scientific developments. New chapters include:* European Regulations* Ethics of Pharmaceutical Medicine* Licensing and Due Diligence* Pharmacogenomics Encompassing the entire spectrum of pharmaceutical medicine, it is the most up...

Since the discovery of the pharmacological and toxicological importance of inhibiting the cyclooxygenase (COX) enzymes by non-steroidal anti-inflammatory drugs (NSAIDs), much research has gone into the development of methods to study the biological functions of COX-1 and COX-2. In Cyclooxygenases: Methods and Protocols, experts and pioneers in the field present the most up-to-date in vitro and in vivo techniques routinely used in COX research. The volume delves into essential topics such as th...

Jetzt kommt Bewegung in die Biochemie! Die ganze Welt der Biochemie und Pathobiochemie in 74 uberschaubaren Kapiteln und uber 1000 Abbildungen erklart - da bleibt keine Frage offen. Und mehr noch, damit Sie die komplexen Vorgange in Stoffwechsel, Signaltransduktion und Molekularbiologie schneller verstehen, sind mit der kostenlosen MoreMediaApp uber 400, teils vertonte Videos direkt aus dem Buch abrufbar - einfach das Bild mit dem Smartphone oder Tablet scannen und schon werden Citratzyklus, D...

This is the first book to present the idea of Industry 5.0 in biomanufacturing and bioprocess engineering, both upstream and downstream. The Prospect of Industry 5.0 in Biomanufacturing details the latest technologies and how they can be used efficiently and explains process analysis from an engineering point of view. In addition, it covers applications and challenges. FEATURES Describes the previous Industrial Revolution, current Industry 4.0, and how new technologies will transition toward I...

Containing contributions from the many disciplines involved in a drug's evolution, this timely volume examines the entire pharmaceutical development process, emphasizing approaches to increasing efficiency and reducing costs.

Microencapsulation has become a promising technology for new applications in fields like drug delivery, biosensing, biomaterials, catalysis, intelligent microstructures and microsystems, as well as in the field of consumer goods. This book is written by authors from academia and industry and aims to present industrial adoption of microcapsules as an innovative solution for problems concerning environmentally-friendly production methods, health protection, and increase of citizen daily life stand...

Human brain made up of billions of neurons; communicate with each other through chemical messengers which are referred to as neuroactive substances. These neuroactive substances include neurotransmitters, neuromodulators, neurohormones and neuromodulators. Some neurotransmitters also act as neuromodulators and neurohormones. It would be cynical if there will ever be general covenant about the meanings of these neuroactive substances including neurotransmitters since the term neurotransmitter has...

As part of its programme for the prevention of health hazards caused by industrial work substances, the Berufsgenossenschaft der chemischen Industrie (BG Chemie) began in 1977 to investigate the toxicity of those substances which are widely used, have many different applications and are suspected of being dangerous to health, in particular those having long-term effects on health. The investigations consist of a literature search and - depending on the results - commissions of experimental studi...

"Summarizes the history of, and available applications, techniques, and approaches to, pharmacogenomics--improving efficacy and tolerance to pharmaceutical compounds, evaluating pharmacogenomics on clinical trial design, and increasing the chances of successful clinical trials and patient outcomes. Compares pharmacogenomics to pharmacogenetics, focusing on the essential components that incorporate individual genetic variations to drug regimens resulting in different responses to therapeutics."

Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.