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The normally functioning cell has controls which prevent it proliferating and invading regions of the body from which it is normally excluded. Under certain conditions, the normal rules breakdown and cell proliferation and migration, or metastasis, leads to the formation of tumours. The metastatic behaviour of malignant tumour cells is responsible for the majority of cancer deaths. This book deals with the behaviour and biochemistry of errant cells, a subject that is at the forefront of current...

The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who ...

The Encyclopedia of Forensic & Legal Medicine comprehensively covers forensic and legal medicine (including related specialities and scientific, technical and legal issues) and is available online and in three printed volumes, offering any practitioner in a forensic, medical, healthcare, legal, judicial, or investigative field easily accessible and authoritative overviews on a wide range of topics. The work is edited and written by experienced professionals with medical, legal or dual traini...

The Maillard reaction, first described during the early 20th century, originally referred to the browning reaction that occurs between amino acids and sugars during the cooking and processing of foods. This reaction contributes to the color, taste, aroma, and texture of foods, and also affects their nutritional and toxicological properties. The Maillard reaction, which has been at the crossroads of food and biomedical sciences, is now also known to contribute to the natural and normal aging of t...

Guest edited by Drs Sarah Vossoughi and Brie Stotler, this issue of Clinics in Laboratory Medicine will cover several key areas of interest related to Pediatric Transfusion Medicine. This issue is one of four selected each year by our series Consulting Editor, Dr. Milenko Tanasijevic. Articles in this issue include but are not limited to: Transfusion in the Pediatric Patient: Review of Evidence Based Guidelines, Transfusion in the Neonatal Patient: Review of Evidence Based Guidelines, Massive Tr...

With increases in the prevalence of psychiatric and behavioral disorders and rapid advances in the development of new drug therapies, there is an increasing need to present the science behind these developments. Students and educators are often confronted with conflicting and exaggerated claims about the effectiveness of drugs. As recently as ten years ago, the mechanisms of action of many medications prescribed for common psychological disorders were not well understood, even by the scientists...

Terminal Ballistics: A Text and Atlas of Gunshot Wounds is a comprehensive guide that explains the science of forensic ballistics - focusing on the hardware, injury patterns, and forensic techniques associated with gunshot wounds. The text begins by describing the anatomy and design of basic firearms and the fundamental components of ammunition rounds, .22 rimfire, and propellants. The author presents a variety of gunshot injury patterns, and defines the concept of the pathological range of fire...

This volume is based on the 10th International Nidovirus Symposium: Towards Control of SARS and other Nidovirus Diseases. The volume includes articles by all of the major contributors to this burgeoning area of research which summarize the work presented at the meeting. This represents the only comprehensive book to cover this field in the last five years.

In den letzten Jahren hat sich der Workshop "Bildverarbeitung fur die Medizin" erfolgreich etabliert. Ziel ist es, aktuelle Forschungsergebnisse darzustellen und den Dialog zwischen Wissenschaftlern, Industrie und Anwendern zu vertiefen. Die Beitrage der Workshop-Dokumentation - einige in englischer Sprache - behandeln alle Bereiche der medizinischen Bildverarbeitung, insbesondere Bildgebung, CAD, Segmentierung, Bildanalyse, Computerunterstutzte Diagnose, Therapieplanung sowie deren klinische An...

Reflects the most significant and fundamental shifts in the experience of disability in human history With the release of its eighth edition, this bestselling text remains the most comprehensive and current text addressing the psychological and social issues dealt with by persons with disabilities. The new edition is almost completely rewritten and expanded by expert voices in disability and rehabilitation policy, research, and lived experience. It presents many new chapters covering topics suc...