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Traditional pharmaceutical development is an unwieldy process requiring extensive experimentation and long lead times before process scientists can fully understand the effect that process parameters such as pH, temperature, cell viability, or process yield may have on the product acceptability. Implementation of quality by design is a science-based approach that allows the operating ranges and the acceptance criteria to be established based on the impact on product quality attributes. During ma...

Offers a detailed introduction to the fundamental phenomena that govern cell adhesion and describes bioengineering processes that employ cell adhesion, focusing on both biochemical and biomedical applications. All industrially relevant issues of cell adhesion - from basic concepts, quantitative experiments, and mathematical models to applications in bioreactors and other process equipment - are examined.

This book describes new strategies being used to combat disease agents and invertebrate pests. Outstanding experts from the United States, Belgium, China, Guatemala, Japan, Philippines, Singapore, and Thailand have contributed chapters that cover the latest achievements in genetic engineering, emphasizing the microbial and viral biological control agents that can provide environmentally safe, economical control systems. Topics discussed include genetic engineering of Bacillus thuringiensis and B...

This research level reference book has been co-written by Enrico Drioli, perhaps one of the world's best known researchers into membrane technology. The application of membrane technology to chemical transformation and molecular separation are beginning to be exploited in the pharmaceutical science and biotechnology industries, but there is a need for researchers and students to have up-to-date literature - and this book provides it. The book will be of interest to students of chemistry, chemica...

This reference book provides advanced knowledge on sustainable biogenic waste management. It covers innovative waste processing technologies to produce biofuels, energy products, and biochemicals. To create a circular bioeconomy, it is imperative to develop processes where the waste generated through one process acts as a feedstock for the other. This book discusses the latest developments in biochemical and thermochemical methods of conversion and covers the potential of different kinds of biom...

Both strategies for investigation (computational and experimental) in structural and mechanistic Enzymology have developed to some extent independently. However, over the last few years a trend has emerged for strengthening their integration. This combination not only brings together computations and experiments focused on the same enzymatic problems, but also provides complementary insights into the investigated properties and has a powerful synergy effect. This thematic volume of Advances in P...

Viral Nanotechnology presents an up-to-date overview of the rapidly developing field of viral nanotechnology in the areas of immunology, virology, microbiology, chemistry, physics, and mathematical modeling. Its chapters are by leading researchers and practitioners, making it both a comprehensive and indispensable resource for study and research. The field of viral nanotechnology is new and quickly expanding due to increasing demand of the applications already developed. The editors identify...

Fundamentals of Light Microscopy and Electronic Imaging, Second Edition provides a coherent introduction to the principles and applications of the integrated optical microscope system, covering both theoretical and practical considerations. It expands and updates discussions of multi-spectral imaging, intensified digital cameras, signal colocalization, and uses of objectives, and offers guidance in the selection of microscopes and electronic cameras, as well as appropriate auxiliary optical syst...

CI Techniques & Algorithms for a Variety of Medical Imaging SituationsDocuments recent advances and stimulates further research A compilation of the latest trends in the field, Computational Intelligence in Medical Imaging: Techniques and Applications explores how intelligent computing can bring enormous benefit to existing technology in medical image processing as well as improve medical imaging research. The contributors also cover state-of-the-art research toward integrating medical image pr...

Plunkett's Biotech & Genetics Industry Almanac is a complete reference guide to the business side of biotechnology, genetics, proteomics and related services. This new book contains complete profiles of the leading biotech companies; in-depth chapters on trends in genetics, technologies, statistics and finances; a handy glossary; and thorough indexes. For the first time, in one carefully-researched volume, you'll get all of the data you need. Topics include: biotechnology funding and investme...

Find out how biotechnology can produce more nutritious fruits and vegetables, more colorful flowers, and grass that needs less waterand mowing!Plant Biotechnology in Ornamental Horticulture presents an in-depth overview of the key scientific and technical advances, issues, and challenges in one of the fastest growing segments of the agriculture industry. This comprehensive book covers 19 different topics related to the use of transgenic plant technology to improve ornamental plants, ranging from...

Exploring aqueous dispersions and solutions, biopolymer gels, self-assembled amphiphillic structures, and interfacial layers of biopolymers and biological cells, this classroom reference presents a concise introductory treatment of the physicochemical principles that determine interrelated colloidal and interfacial phenomena. Whether deciphering the spontaneous assembly of amphiphilic molecules or the intentional fouling of surfaces for the immobilization of cells in bioreactors, the book devote...

The six years that have passed since the publication of the first edition have brought significant advances in both biofilm research and biofilm engineering, which have matured to the extent that biofilm-based technologies are now being designed and implemented. As a result, many chapters have been updated and expanded with the addition of sections reflecting changes in the status quo in biofilm research and engineering. Emphasizing process analysis, engineering systems, biofilm applications, an...

In the post-genomic era SAGE (Serial Analysis of Gene Expression) is one of the most powerful tools available for global expression profiling at the mRNA level (transcriptome analysis). SAGE is also a valuable tool for gene discovery and gene network identification. Written by recognized experts in the field, this timely and authoritative volume reviews every aspect of SAGE technology including the evaluation of SAGE, the improvement and further development of SAGE methodology, the statistical a...

Significant progress has been made in gene technology and skin gene therapy in the last few years. Besides the development of suitable animal models, novel molecular technologies such as small inhibitory RNA are discussed, which enable the modification of sequence-specific gene expression. Progress is reported in the field of DNA vaccination against HIV-1 as well as in the correction of xeroderma pigmentosum using retroviral-based gene transfer. In addition to gene technology and skin gene thera...

Highlights the impact of biotechnology on the food industry and discusses strategies for producing new and improved raw materials. Details the latest analytical methodology for characterizing products generated by biotechnology. Describes the generation of flavours from precursors via enzymes and microorganisms. Discusses the construction of chimeric enzymes with improved properties. Reviews the effect of new plant crop regulators on crop yield and quality.

This book, written by a leading geneticist, examines the ethical and social issues raised by the genetic testing of children. The opinions of geneticists, ethicists and affected families are all included to give a balanced view of this controversial field. Issues covered include confidentiality, potential abuses of genetic information (eg the use of test results by insurance companies) and the value of predictive genetic testing. The aim of the book is to improve awareness of the complexity of t...

A completely new practical guide to both new and classical methods of slide-making which is easy-to-read and easy-to-understand. Biological Microtechnique contains a wealth of practical detail which will provide a firm grounding in preparative methods for light microscopy.

The new edition of Biotechnology: Science for the New Millennium is the perfect textbook and lab manual combination program for your classroom! Designed for introductory courses, this complete program teaches the concepts and hands-on lab procedures required for entry-level careers in the rapidly growing biotechnology industry. The textbook and lab manual can be used together or separately, depending on the desired course format.