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Synthetic biology encompasses a vast array of research, from creating artificial life to engineering microbes, in order to produce medicines or fuels. Throughout it all, chemistry plays a prominent part. This book reviews the emerging field of synthetic biology in an interdisciplinary manner. The current status of the field is discussed, illustrating a quantitative approach to design which exemplifies and builds novel biological arrangements to carry out unique tasks with a chemical and engineer...

Conventional computed tomography (CT) techniques employ a narrow array of x-ray detectors and a fan-shaped x-ray beam to rotate around the patient to produce images of thin sections of the patient. Large sections of the body are covered by moving the patient into the rotating x-ray detector and x-ray source gantry. Cone beam CT is an alternative technique using a large area detector and cone-shaped x-ray beam to produce 3D images of a thick section of the body with one full angle (360 degree or...

Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentation, Second Edition helps biomedical engineers understand the basic analog electronic circuits used for signal conditioning in biomedical instruments. It explains the function and design of signal conditioning systems using analog ICs—the circuits that enable ECG, EEG, EMG, ERG, tomographic images, biochemical spectrograms, and other crucial medical applications. This book demonstrates how op amps are the keystone...

The development and application of assistive technology can help those with reduced abilities improve their quality of life and reduce their dependence on others. Written in layman's terms, Devices for Mobility and Manipulation for People with Reduced Abilities provides research and information on assistive technologies for non-technical people. While it highlights various mobility and manipulative technologies, with the exception of specific examples within the text, it keeps technical terminol...

With no emissions and water as a byproduct, the globe could imagine a sustainable and resilient human kind that obliterates any possible chances of future climate change. With increased globalization, there has been an unprecedented escalation in production processes thus generating valued products and byproducts. A significant quantum of the waste materials generated can be transformed into fuels with the help of MFCs. MFC's utilities would bring about a paradigm shift built on the principles o...

Merging topical data from recently published review and research articles, as well as the knowledge and insight of industry experts, Omics Applications in Crop Science delves into plant science, and various technologies that use omics in agriculture. This book concentrates on crop breeding and environmental applications, and examines the applications of various omics technologies including genomics, transcriptomics, proteomics, metabolomics to important agronomic, horticultural, medicinal, plant...

Software is one of the most important products in human history and is widely used by all industries and all countries. It is also one of the most expensive and labor-intensive products in human history. Software also has very poor quality that has caused many major disasters and wasted many millions of dollars. Software is also the target of frequent and increasingly serious cyber-attacks. Among the reasons for these software problems is a chronic lack of reliable quantified data. This referen...

Applied Genomics and Public Health examines the interdisciplinary and growing area of how evidence-based genomic knowledge can be applied to public health, population health, healthcare and health policies. The book gathers experts from a variety of disciplines, including life sciences, social sciences, and health care to develop a comprehensive overview of the field. In addition, the book delves into subjects such as pharmacogenomics, genethics, big data, data translation and analysis, eco...

This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evid...

From cell phones to treating cancer, EM energy plays a part in many of the innovations that we take for granted everyday. A basic force of nature, like nuclear energy or gravity, this energy can be harnessed and used, but still holds the potential to be harmful. The question remains, how safe are EM products? Bioeffects and Therapeutic Applications of Electromagnetic Energy provides a review of cutting-edge research in EM health effects and EM therapy along with emerging areas of bioengineering...

This book describes at the introductory level how modern technology has made the scenario of the classic science-fiction movie Fantastic Voyage a reality. The movie is about a submarine and its crew members being shrunk to microscopic size and ventured into the body. Exactly 50 years following the release of the film, such reality takes the form of a medical interventional room capable of mimicking this scenario. Based on 15 years of intensive research and development by the world-leading team i...

Nanotechnology is a budding field and has a pivotal role in sensing. Nanomaterials exist in various forms such as nanoparticles, nanoclusters, nanobelts, and nanospheres. These nanomaterials act as sensing interfaces and immobilization surfaces for various biomolecules such as enzymes, DNA, and antigens. Therefore, the preparation and characterization of these nanoparticles play an important role in sensing devices. This handbook has evolved from the authors’ teaching and research experience i...

Tissue engineering uniquely applies concepts and techniques from biology and engineering in order to heal or produce new tissues after disease or traumatic injury. A successful tissue engineer must have knowledge of cellular biology, cell signaling, extracellular matrix development, and tissue structure and integrate it with the application of stresses and strains, mass transfer, mechanical properties, and heat transfer. In order to train the next generation of successful tissue engineers, this...

Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the efficacy and nature of interactions between nucleic acids and their putative ligands. This progress can benefit tremendously from new methods that probe...

Lung cancer remains the leading cause of cancer-related deaths worldwide. Early diagnosis can improve the effectiveness of treatment and increase a patient’s chances of survival. Thus, there is an urgent need for new technology to diagnose small, malignant lung nodules early as well as large nodules located away from large diameter airways because the current technology—namely, needle biopsy and bronchoscopy—fail to diagnose those cases. However, the analysis of small, indeterminate lung masses...

Significant advancements in nutrition's impact on the eye have occurred faster than any volume can document... until now. This book gives the background and rationale regarding the physiological damage caused by biological oxidants as well as the rationale for the protective roles for nutrient-antioxidants and how they affect the risk for cataracts. This volume also contains information on how to quantitatively assess age-related diseases of the eye including cataracts and age-related maculopat...

3D printing is revolutionizing manufacturing from basic machine tools up to and including housing. Medical device manufacturing also is very much a part of this innovation. This book details the current and latest practices in 3D printing for the medical device industry. Each chapter is written by outstanding practitioners and technicians in this rapidly emerging field. The editor, Ted Kucklick, is one of industries' leading authorities in medical device design, testing, and fabrication.

The emerging paradigm of incorporating images and biomechanical properties of soft tissues has proven to be an integral part of the advancement of several medical applications, including image guided radiotherapy and surgery, brachytherapy, and diagnostics. This expansion has resulted in a growing community of medical, science, and engineering professionals applying mechanical principles to address medical concerns. This book is tailored to cover a range of mechanical principles, properties, and...

This is a comprehensive treatment of the field of SPR sensors, in three parts. Part I introduces principles of surface plasmon resonance bio-sensors, electromagnetic theory of surface plasmons, theory of SPR sensors and molecular interactions at sensor surfaces. Part II examines the development of SPR sensor instrumentation and functionalization methods. Part III reviews applications of SPR biosensors in the study of molecules, and in environmental monitoring, food safety and medical diagnostics...

Two of the most important yet often overlooked aspects of a medical device are its usability and accessibility. This is important not only for health care providers, but also for older patients and users with disabilities or activity limitations. Medical Instrumentation: Accessibility and Usability Considerations focuses on how lack of usability and accessibility pose problems for designers and users of medical devices, and how to overcome these limitations. Divided into five broad sections, th...

The key role played by iron, as well as other transition metals, in microbial metabolism is investigated in this volume. Topics covered include: iron chelation and siderophores; receptor-mediated bacterial iron transport; and the nitogenases.

This book highlights the characteristics, aims, and applications of bionanotechnology as a possible solution for sustainable management and bioremediation of environmental pollutants. It covers remediation of toxic pollutants, removal of emerging contaminants from industrial wastewater, eco-design and modification study of bio-nanoparticles and life-cycle assessment, nano-filtration, bio-nanomaterials based sensors for monitoring air and water pollution, resource recovery from wastewater, and hi...