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The last four decades of medical engineering have witnessed dramatic strides in mechanical support for heart failure patients, yet the medical literature is sorely lacking a comprehensive, up-to-date examination of these improvements and the current state of the field. Filling this gap, this book covers the clinical, technical, design, and relevant engineering aspects of all currently available mechanical circulatory devices. It offers a short synopsis of the historical development of this life-...

Foreseeing and planning for all of the possibilities and pitfalls involved in bringing a biotechnology innovation from inception to widespread therapeutic use takes strong managerial skills and a solid grounding in biopharmaceutical research and development procedures. Unfortunately there has been a dearth of resources for this aspect of the field.

Human Computer Interface Technologies for the Motor Impaired examines both the technical and social aspects of human computer interface (HCI). Written by world-class academic experts committed to improving HCI technologies for people with disabilities, this all-inclusive book explores the latest research, and offers insight into the current limitations of this field. It introduces the concept of HCI, identifies and describes the fundamentals associated with a specific technology of HCI, and prov...

In recent decades, dendrimers - free-shaped synthetic macromolecules - have garnered a great deal of scientific interest because of their unique molecular nanostructure. Used in a variety of scientific applications, dendrimers are now widely regarded as a safer, more precise and more effective way to practice medicine. This book compiles and details cutting-edge research in science and medicine from the interdisciplinary team of the Michigan Nanotechnology Institute for Medicine and Biological...

There is already a wealth of literature covering cumulative trauma disorders and medical management, as well as the biomechanics of manual material handling and lower back problems. However, despite a spike in the number of work-related musculoskeletal disorders (WRMSDs) in the upper limbs—due to a sharp increase in the amount of computer-related jobs—few if any books have focused exclusively on WRMSDs, until now. Biomechanics of the Upper Limbs: Mechanics, Modeling and Musculoskeletal Injuries...

This unique handbook (60 chapters) examines the entire "product life cycle," from the creation of nanomedical products to their final market introduction. While focusing on critical issues relevant to nanoproduct development and translational activities, it tackles topics such as regulatory science, patent law, FDA law, ethics, personalized medicine, risk analysis, toxicology, nano-characterization and commercialization activities. A separate section provides fascinating perspectives and editori...

This book relates to the analysis and the development of methods to for a nerve-machine interface. Peripheral nerves, both somatic and autonomic, carry signals related to control and the status of the organs. Nerves are made up of many fascicles, each surrounded by protective membranes. The goal is to provide a theoretical and experimental understanding of how one can recover neural signals from the various fascicles or selectively control the activation of these fascicles.

This book is dedicated to the field of conductive polymers, focusing on electrical interactions with biological systems. It addresses the use of conductive polymers as the conducting interface for electrical communications with the biological system, both in vitro and in vivo. It provides an overview on the chemistry and physics of conductive polymers, their useful characteristics as well as limitations, and technologies that apply conductive polymers for medical purposes. This groundbreaking re...

Filling the need for a lab textbook in this rapidly growing field, A Laboratory Course in Tissue Engineering helps students develop hands-on experience. The book contains fifteen standalone experiments based on both classic tissue-engineering approaches and recent advances in the field. Experiments encompass a set of widely applicable techniques: cell culture, microscopy, histology, immunohistochemistry, mechanical testing, soft lithography, and common biochemical assays. In addition to teaching...

The goal of biomimetic chemistry is to create molecules that function in similar ways to what is observed in nature. The subject is gaining attention because of its applications to, for example, artificial photosynthesis, biomaterials, and membranes. Because it tries to reproduce bioprocesses through synthetic chemistry, biomimetic chemistry is closely allied with chemical evolution, which has long been a topic of interest to astrochemists, geologists, and nuclear scientists. Exploring the conne...

Highlighting the human applications of the science, this volume discusses the fundamental concepts and underlying science of bionanotechnology, and the bionanomachines that result from research into this exciting new field. Distilling the authors' research and groundbreaking original experimentation, chapters cover bionanomachines and their use with and manipulation of DNA, RNA, proteins, carbohydrates, and lipids. Well-documented and authoritative, this book offers students and scientists alike...

Capturing the growth of the global medical device market in recent years, this practical new guide is essential for all who are responsible for ensuring safety in the use and manufacture of medical devices. It has been extensively updated to reflect significant advances, incorporating combination products and helpful case examples of current real-life problems in the field. The Third Edition explores these key current trends: global device marketscontinually advancing technologythe increasing h...

Theoretically capable of separating tens of thousands of proteins, two-dimensional gel electrophoresis (2DGE) is often still regarded as procedurally complex and poorly reproducible. An indispensible tool that enables even inexperienced researchers to obtain reliable, highly reproducible separations of protein by 2DGE, this "pocket guide" is a valuable resource for detailed protocols, professional "secrets for success", buffer recipes, and troubleshooting guides that reflect the recognized exper...

Mostindustrialbiotechnologicalprocessesareoperatedempirically.Oneofthe major di?culties of applying advanced control theories is the highly nonlinear nature of the processes. This book examines approaches based on arti?cial intelligencemethods,inparticular,geneticalgorithmsandneuralnetworks,for monitoring, modelling and optimization of fed-batch fermentation processes. The main aim of a process control is to maximize the ?nal product with minimum development and production costs. This book is in...

This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engine...

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent resear...

Major and exciting changes have taken place recently in various aspects of bio- technology and its applications to forestry. Even more exciting is the prospect of major innovations that the entire field of biotechnology holds for plant growth in general. The importance of these developments for the forestry sector is considerable, particu- larly since forestry science has not received the kinds of technical and R&D inputs that, say, agriculture has received in the past few decades. Y ct the prob...

Integrated Mechanics Knowledge Essential for Any Engineer Introduction to Engineering Mechanics: A Continuum Approach, Second Edition uses continuum mechanics to showcase the connections between engineering structure and design and between solids and fluids and helps readers learn how to predict the effects of forces, stresses, and strains. The authors’ "continuum checklist" provides a framework for a wide variety of problems in solid and fluid mechanics. The essence of continuum mechanics, the...

The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory...

Biomimetics is based on nature, while technology is based on economy. One of the solutions for a sustainable society is to learn a grand design of technology from nature. Methods that mimic nature have a long history in various fields. Now is the time to use biomimetics as a starting technology design. Biomimetics is gaining a great deal of attention not only in materials and mechanical engineering but also in the ecosystem that comprises city planning, agriculture, and forestry. Informatics is...

This book presents a wide range of tested and proven protocols relevant to a number of fields within biotechnology used in laboratory experiments in everyday phycological (seaweed) research. A major focus will be on bioenergy related aspects of this emerging technology. These protocols will be written in a clear and concise manner using simple language permitting even nonspecialist to adequately understand the significance of this research. It will also contain all necesssary notes and guideline...