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"Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it's estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-...

As a scientist, David Linden had devoted his career to understanding the brain processes and behaviors that are common to us all. That is, until a few years ago, when he found himself on OKCupid. Looking through that vast catalog of human difference, he got to thinking, where does it all come from? Why does one person have perfect pitch, a taste for hoppy beer, and an aversion to bathroom selfies? That is, what makes you, you, and me, me?In Unique, David Linden tells a riveting and accessible st...

The oocyte is the largest and most mysterious cell in the body of mammalian organisms. Through its growth and maturation, it reaches extreme levels of specialization, while maintaining at the same time a condition of totipotency. Its unique ability, in co-operation with the spermatozoon, to give rise to a fully developed organism formed from hundreds of different tissues and myriads of individual cells has inspired intellectuals of all ages. Oogenesis finds impetus and purpose in casting scient...

Una guía única para comprender la diabetes y aprender cómo vivir (y vivir bien) con ella. Aunque haya datos acerca de ella desde hace siglos, es en los últimos años que la diabetes ha empezado a ocupar un espacio mayor en las conversaciones sobre salud pública. No por nada se trata, hoy en día, de una de las enfermedades crónicas no contagiosas y sin cura más frecuentes del mundo. Solamente en España, se calcula que afecta a más de seis millones de personas y que su tasa de incidencia es cada...

Communication between cells via intercellular channels – gap junctions – appears essential to certain developmental processes and appropriate organ function. Gap Junctions in Development and Disease aims to describe the molecular events underlying impaired development and disease. Beginning with a comprehensive review of various mouse and human genes encoding the channel-forming connexins, later chapters describe several connexin mutations associated with human diseases such as hereditary deafne...

Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of...

Nigel has a disability - an inherited disease that means his nerves don't tell his muscles what to do - but he does not consider himself disabled. His youngest daughter Ellie has been diagnosed with the same condition. To inspire Ellie, and show her anything is possible, Nigel set himself a list of fifty challenges. This is the story of that list. Nigel and his wife Lisa have three children and, like all parents, they have always wanted the best for their kids. For Nigel, this meant he...

Un relato honesto y desgarrador sobre la pérdida de un hijo y la confianza en que la muerte no separa a las almas de los seres queridos En este libro conmovedor, la actriz chilena Leonor Varela, quien vive actualmente en Estados Unidos, relata la historia vivida con su hijo Matteo, diagnosticado leucodistrofia AGS (Leukodystrophy AGS) a los cuatro meses de vida. Jamás aceptó el diagnóstico de los médicos y emprendió una lucha física, emocional y espiritual para salvarle la vida. En el camino...