This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety and pharmacokinetic features in preclinical (using in vitro and in vivo models) and clinical experimentation to identifying future drug targets. Containing up-to-date experimental evidence and detailing the main impediments in the pipeline of CNS drug discovery and development, this is a key reference for those involved in all stages of CNS drug discovery.Key Features:
- Discusses in detail the key stages of CNS drug discovery, outlining the particular requirements and obstacles for CNS drugs
- Addresses safety concerns and future drug targets
- Provides succinct background information about the major CNS diseases
- Examples of specific drugs are used throughout to describe the development of a new drug from conception to clinical use and post-market surveillance
- Primary reasons for drug failure are given for each stage
- ISBN10 0470519797
- ISBN13 9780470519790
- Publish Date 12 January 2010 (first published 13 November 2009)
- Publish Status Active
- Publish Country US
- Imprint John Wiley & Sons Inc
- Format Hardcover
- Pages 324
- Language English