Neuroscientists have long recognized the importance of understanding the underlying principles of information processing by large populations of neurons. Methods for Neural Ensemble Recordings explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. Since current methods allow one to simultaneously record the extracellular activity of up to 100-150 neurons for days or even weeks, neural ensemble recordings have been used to address long-standing issues in development, learning, memory, sensorimotor integration, sensory information processing, and neuronal plasticity.
EXAMINES THE MANY POSSIBLE APPLICATIONS FOR THIS REVOLUTIONARY METHOD
Each chapter offers a step-by-step description for the implementation of a particular technique or experimental paradigm employing simultaneous multiple electrode recordings. The techniques described can be used in applications that impact a large group of life scientists, including:
drug screening (pharmacology) in both in vitro and in vivo preparations
developmental studies and studies of neuronal plasticity
chronic monitoring of neuronal function in behavioral studies
physiological monitoring of neuronal activity in cell cultures and brain slices
physiological monitoring of neuronal activity in neurons trafected with genetic vectors
chronic monitoring of physiological changes in populations of neurons during learning of new sensorimotor and cognitive tasks
- ISBN10 0849333512
- ISBN13 9780849333514
- Publish Date 23 December 1998
- Publish Status Unknown
- Out of Print 2 October 2008
- Publish Country US
- Publisher Taylor & Francis Inc
- Imprint CRC Press Inc
- Format Hardcover
- Pages 272
- Language English