Epithelial cells cover the outer abd inner surfaces of the body, forming a selective polarized barrier between the intercellular space and the 'external' world. Linking the cells of this continuous layer and contributing to epithelial organization and function are specialized membrane domains- desomes, gap junctions and occluding junctions.The contributors to this multidisciplinary symposium volume explore the nature of such junctional structures, focusing on the molecular organization and diversity of their constituent proteins, their formation and control, and interactions with ions and cytoskeletal elements. The physiological significance of cell-cell interaction in epithelia is considered, with reference to cell adhesion, barrier formation and intracellular communication and to the functional implications for tissue architecture, embryonic development, morphogenesis and carcinogenesis.
- ISBN10 6612122331
- ISBN13 9786612122330
- Publish Date 4 February 1987 (first published 21 January 1987)
- Publish Status Active
- Out of Print 28 August 2012
- Publish Country US
- Imprint John Wiley & Sons
- Format eBook
- Pages 283
- Language English