This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion.
As a result, this key resource lays the foundations for understanding and investigating the molecular mechanisms for multidrug resistance in cancer cells, microbial resistance to antibiotics and pharmacokinetics in general.
For anyone working with antibiotics and cancer chemotherapeutics, as well as being of prime interest to biochemists and biophysicists.
- ISBN10 3527316612
- ISBN13 9783527316618
- Publish Date 14 October 2009 (first published 1 September 2009)
- Publish Status Out of Print
- Out of Print 31 October 2023
- Publish Country DE
- Publisher Wiley-VCH Verlag GmbH
- Imprint Blackwell Verlag GmbH
- Format Hardcover
- Pages 449
- Language English