Johnson's book describes the effects of genetic mutations on the mammalian skeleton, and their usefulness as a tool to help us understand how the skeleton develops. Using the mouse as a primary source, but with mutations in other laboratory animals discussed where appropriate, the author considers the precartilaginous (mesenchymal), cartilaginous, and bony skeletons, regional anatomy (axial and appendicular skeletons, the skull, face, palate, and teeth), and the interactions between genes and teratogens. Each chapter consists of a summary covering the development of a particular area or topic, followed by a consideration of mutants and how they affect the area. A short synthesis discusses the contributions that mutants make to our understanding of the development of each area considered.
- ISBN10 0198541635
- ISBN13 9780198541639
- Publish Date 18 September 1986
- Publish Status Out of Print
- Out of Print 18 May 2000
- Publish Country GB
- Imprint Oxford University Press
- Format Hardcover
- Pages 422
- Language English