Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry, #29)

by D.J. Triggle

David J Triggle (Editor), Andreas Ziegler (Editor), David Rampe (Editor), Wei Zheng (Editor), Raimund Mannhold (Editor), Hugo Kubinyi (Editor), Gerd Folkers (Editor), and Murali Gopalakrishnan (Editor)

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Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
  • ISBN10 1280723459
  • ISBN13 9781280723452
  • Publish Date 1 January 2006
  • Publish Status Active
  • Out of Print 17 February 2015
  • Publish Country US
  • Imprint Wiley-Vch
  • Format eBook
  • Pages 479
  • Language English