This book is primarily a handbook for those scientists interested in using tritium NMR spectroscopy. It covers the development and use of the technique, which is the only non- destructive method available for the routine determination of labelling patterns in tritium labelled compounds, essential tools for research in the life sciences. The book highlights the uses of the technique not only for determining the positions of labels but also in understanding catalysed hydrogen isotope exchange reactions, the function and mechanism of action of catalysts, reaction mechanisms and isotope effects. Environmental chemistry, radiation chemistry and other analytical applications involving the use of tritium labelled compounds as tracers are also described. A comprehensive review of tritium NMR spectroscopy is provided in the three chapters of the text which discuss experimental aspects, labelling patterns and methods for tritium labelling, and applications of tritium NMR spectroscopy.
Many scientists interested in this book may not have direct access to an NMR instrument capable of producing tritium NMR spectra but they will find useful the many examples of the spectra obtained from a number of methods of tritiation which for convenience are given in tabular form grouped under compound type. In these tables the authors have attempted to include all the tritium NMR assignments reported in the literature and a wealth of their own material. For the increasing number of groups who are using this technique the book provides a full theoretical background as well as practical guidance.
- ISBN10 0471905836
- ISBN13 9780471905837
- Publish Date 22 May 1985
- Publish Status Out of Print
- Out of Print 31 July 1997
- Publish Country GB
- Publisher John Wiley and Sons Ltd
- Imprint John Wiley & Sons Ltd
- Format Hardcover
- Pages 264
- Language English