The Smallpox Files

by Ruth Redford

Published 18 September 2025
Marnie's teacher has a unique assignment for the class--learn all they can about a disease that has been eradicated, smallpox! Marnie teams up with her friend SJ and her trusty AI sidekick Glitch to gather the information. What was smallpox and how did it spread? How did scientists use inquiry and the tools of science to solve the mystery of smallpox? Finally, Maisie and her classmates learn how scientists were able to wipe out the disease, and how we're protected from smallpox today.

Marnie's Medical Mysteries was developed in collaboration with Nipunie Rajapakse, M.D., pediatric infectious diseases physician at the Mayo Clinic Children’s Center.

A fun graphic approach, diverse characters, and humorous text tell this thrilling story of medical history in a high-interest format.

Mayo Clinic Press Kids creates empowering health and wellness content in partnership with pediatric experts. Proceeds from the sale of every book go to benefit important medical research and education at Mayo Clinic.