This publication is the fifth in the IAEA Nuclear Energy Series to provide guidance on the inclusion of safeguards in nuclear facility design and construction. It is principally intended for designers and operators of facilities for long term spent fuel; however, vendors, national authorities and financial backers can also benefit from the information provided. The publication complements the general considerations addressed in International Safeguards in Nuclear Facility Design and Construction, IAEA Nuclear Energy Series No. NP-T-2.8.