v. 9

Molecular Neurobiology of Epilepsy reflects the rapid expansion of this exciting new area of neuroscience and provides a forum for the exchange of information betweeen investigators currently studying epileptic phenomena at the membrane, cellular and systems levels, using physiological, biochemical, anatomical, and clinical approaches, and molecular neurobiologists concerned with basic mechanisms of normal neuronal growth, development, and plasticity, that might, when disrupted, explain the appearance of epileptic hyperexcitability and hypersynchronization. The book contains three sections, the first devoted to cellular defects in early and late brain development, the second to injury-related neuronal growth and death, and the third to activity-induced genetic expression and synaptic plasticity. This valuable volume therefore points to new areas of basic research on epilepsy, as well as new concepts for therapeutic and preventive clinical interventions.