A mysterious illness is spreading rapidly through the halls of Fujimi High School. In a matter of hours, the campus is transformed from a place of learning into a hive of nightmares, as the infected students collapse and are reborn as flesh-hungry zombies! Only a handful of students escape the initial outbreak - among them Takashi Komuro and his childhood friend, Rei. He manages to protect Rei from the initial onslaught, but how long can Takashi and the other students hope to survive when the whole school - maybe the whole town - is out for their blood?!
Separated from the rest of the survivors from their high school, Takashi and Rei make their way through town, taking in the full scope of the sudden outbreak that's turned most of the residents into undead terrors. Though the immediate threat of attack has subsided, their survival instinct is still on high alert. Among those untouched by the disease, anarchy is the only law, and when anything goes, Takashi and Rei may have to become monsters themselves if they want to stay alive.
The high school escapees are joined by elementary-schooler Alice and a brave little dog as they make their way to the next safe house, not a soul (or corpse) in sight. The Alice's presence eases the tension, but as Marikawa-sensei drives farther into the neighborhood, 'they' seem to be out in greater numbers. The car struggles to shake the relentless zombies while Takashi and Rei cling perilously to the roof. The group has been lucky so far, but will their determination and makeshift arsenal be enough to make it to safety alive?
As fear becomes the norm and people begin to process what has happened, questions of authority and outcries against violence toward 'them' - the zombie-like victims of the 'Murder Syndrome' - cause dissent among those not affected. However, trapped in the airport with thousands of flesh-hungry undead, Rika and her partner have no choice but to use every weapon in their arsenal if they want to make it to safety. But with neighbor turning on neighbor, nation turning against nation, is anywhere really safe anymore?
Once again, Takashi and his friends are without shelter and on the run. The group gradually makes their way to the local police station, where the hungry officers within give a whole new meaning to the phrase 'police brutality.' After tidying up, the team reloads and begins their search of the station: Rei for news of her father, and Saya for information. There may be one last chance for them to get out of town, but with Rei and Takashi's parents still unaccounted for and a throng of undead standing between them and freedom, will the friends be able to make it in time?!
As the mall refugees grow restless, Takashi and his comrades make plans to leave before Officer Asami's authority slides further and the group's order is completely undone. Unfortunately, just as final preparations for their departure are nearly complete, the mall's defenses are breached, and 'they' come streaming in. Asami joins the Fujimi High students as they battle their way toward the exit, while the rest of the group seeks refuge on the roof. Their fortress has become a trap - can anyone hope to escape the mall of the dead?!
Takashi and his fellow students join up with a band of survivors who have barricaded themselves inside a local mall. Though the shopping center seems a well-stocked place to hide from the undead lurking outside, the policewoman in charge is having a hard time maintaining peace within. The group from Fujimi High would rather not get involved in a power struggle and tries to stay under the radar until they are ready to set off again. But with so many attractive, buxom girls among the students, it may be nearly impossible to avoid unwanted attention of the worst kind...