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Cover of Lectins and Glycobiology

Lectins and Glycobiology

Published 27 October 1993
The role of lectins and glycoconjugates in various cellular processes is receiving increased interest. Since many cellular glycoconjugates are ligands for lectins, they are used as efficacious tools in biochemistry and cell research. This volume provides all of the relevant techniques to investigate the structure and function of lectins and their various reactions. Included are methods for the preparation of synthetic carbohydrate ligands, the determination of physico-chemical properties of lectin-oligosaccharide interactions, the isolation and chemical modification of lectins, and assays to detect and quantitate lectins. Several chapters focus on the study of signal transduction and cellular responses induced by lectins as well as on cellular adhesion and cell recognition involving lectin-glycoprotein interaction. Further major topics are molecular biological techniques such as the use of recombinant or mutant lectin genes.