Restored to life by popular demand after his last struggle with Professor Moriarty at the Reichenbach Falls, Sherlock Holmes dons his deerstalker again for twelve final adventures. With the affable Dr. Watson at his side, he employs pipe, violin and, of course, his astounding methods of scientific deduction, to solve the unsolvable in mysterious cases, including "The Adventure of the Sussex Vampire", "The Adventure of the Creeping Man" and "The Adventure of the Veiled Lodger".

To the police it is a formidable case and they are grateful for the razor brain of the great detective Sherlock Holmes. There are perplexing details - wedding ring missing together with one dumb-bell, the odd behaviour of the widow and a card inscribed VV 341 lying by the faceless body.