SpringerBriefs in Applied Sciences and Technology

1 total work

Proliposomes: A Manufacturing Technology of Liposomes for Pulmonary Delivery via Nebulization

by Abdelbary Elhissi, Waqar Ahmed, Kevin M.G. Taylor, Xun Sun, Zhi-Rong Zhang, and David A. Phoenix

Published 23 December 2022

Proliposome technologies are stable phospholipid formulations that provide an approach to generating liposomes upon addition of aqueous phase prior to administration. In this monograph, the authors review the potential of proliposomes for pulmonary delivery of liposomes via nebulization using air-jet, ultrasonic and vibrating-mesh nebulizers. They explore both proliposome types, particulate-based and solvent-based. The book concludes that both types are capable of exploiting the energy of nebulization to generate liposomes within nebulizers.