The IACUC Handbook, Third Edition
Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution’s IACUC. It provides a founda...
Multiplicity in Clinical Trails (Chapman & Hall/CRC Biostatistics)
by Frank Bretz, Willi Maurer, and Michael Branson
Introductory Biostatistics for the Health Sciences
by Robert C. Duncan and etc.
Management of Animal Care and Use Programs in Research, Education, and Testing
AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable sem...
Bioreactor Systems for Tissue Engineering (Advances in Biochemical Engineering/Biotechnology, #112)
The editors of this special volume would first like to thank all authors for their excellent contributions. We would also like to thank Prof. Dr. Thomas Scheper, Dr. Marion Hertel and Ulrike Kreusel for providing the opportunity to compose this volume and Springer for organizational and technical support. Tissue engineering represents one of the major emerging fields in modern b- technology; it combines different subjects ranging from biological and material sciences to engineering and clinical...
Insect Biotechnology (Biologically-Inspired Systems, #2)
The book provides a fascinating overview about current and sophisticated developments in applied entomology that are powered by molecular biology and that can be summarized under a novel term: insect biotechnology. By analogy with the application of powerful molecular biological tools in medicine (red biotechnology), plant protection (green biotechnology) and industrial processing (white biotechnology), insect biotechnology (yellow biotechnology) provides novel tools and strategies for human we...
The Laboratory Small Ruminant details basic information and common procedures for individuals performing research with small ruminants. Details include duties of animal husbandry, regulatory compliance, and technical procedures. It is designed to assist in the humane care and use of small ruminants in the laboratory and to provide immediate information for investigators, technicians, and animal caretakers. It includes references to alternative procedures and methods and offers possible sources a...
Laboratory Rat Procedural Techniques
by John J. Bogdanske, Scott Hubbard-Van Stelle, Margaret Rankin-Riley, and Beth M. Schiffman
This combination manual and downloadable resources provide much-needed training on the proper handling of rats used in biomedical research. The downloadable resources include narrated video clips that demonstrate and describe each procedural technique. The manual contains handouts with color illustrations and descriptive text for each technique, including the purpose and application of the procedure, recommended skills, and necessary supplies. It can be used as a training resource and refresher...
Score your highest in biostatistics Biostatistics is a required course for students of medicine, epidemiology, forestry, agriculture, bioinformatics, and public health. In years past this course has been mainly a graduate-level requirement; however its application is growing and course offerings at the undergraduate level are exploding. Biostatistics For Dummies is an excellent resource for those taking a course, as well as for those in need of a handy reference to this complex material. Biostat...
Dr. Hilary Koprowski is the pioneer of live polio vaccine, the first researcher to advance the diagnostic and therapeutic use of monoclonal antibodies, and the developer of the "gold standard" rabies vaccine. This biography chronicles his distinguished career and life's work in the field of microbiology. A world-reknowned maverick in biomedical research, Koprowski's research methods were often considered controversial and even radical. Nonetheless, he acquired key positions in many research orga...
Mouse Development (Results and Problems in Cell Differentiation, #55)
The mouse is a perfect model organism to study mammalian, and thus indirectly also human, embryology. Most scientific achievements that have had an important impact on the understanding of basic mechanisms governing embryo development in humans, originated from mouse embryology. Stem cell research, which now offers the promise of regenerative medicine, began with the isolation and culture of mouse embryonic stem cells by Martin Evans (who received the Nobel Prize in medicine in 2007 for this ach...
Protein Phosphatases (Topics in Current Genetics, #5)
This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes. The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the ph...
This text provides researchers with descriptions and explanations of the concepts and methods used in qualitative research. With the move towards evidence-based practice and emphasis placed on multidisciplinary research teams, there is a growing use of qualitative research methods. Qualitative research looks at processes as well as outcomes and enables data to be gathered on a range of human experience, taking a person-centred and holistic approach. The book's entries are ordered alphabetically...
During the past 20 years, transgenesis has become a popular technique and a crucial tool for molecular geneticists and biologists. Transgene expression is now better-controlled and even specifically inducible by exogenous factors. While these techniques have quite significantly transformed the experimental approaches taken by biologists, the applications are more limited than expected and concerns have arisen regarding biosafety as well as physiological, social, and philosophical issues. Transge...
Biodefense Research Methodology and Animal Models
Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA's Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Resea
This book provides essential worldwide reference information regarding rabies for public health officials, veterinarians, physicians, virologists, epidemiologists, infectious disease specialists, laboratory diagnosticians, and wildlife biologists. The book is divided into six main sections, covering topics such as the rabies virus, including antigenic and biochemical characteristics; pathogenesis, including the immune response to the infection, pathology, and latency; diagnostic techniques; rabi...
Fractals’ Physical Origin and Properties
This volume contains the Proceedings of the Special Seminar on: FRAGTALS held from October 9-15, 1988 at the Ettore Majorana Centre for Scientific Culture, Erice (Trapani), Italy. The concepts of self-similarity and scale invariance have arisen independently in several areas. One is the study of critical properites of phase transitions; another is fractal geometry, which involves the concept of (non-integer) fractal dimension. These two areas have now come together, and their methods have extend...
Molecular Modeling of Proteins (Methods in Molecular Biology, #443)
Molecular Modeling of Proteins, Second Edition provides a theoretical background of various methods available and enables non-specialists to apply methods to their problems by including updated chapters and new material not covered in the first edition. This detailed volume opens by featuring classical and advanced simulation methods as well as methods to set-up complex systems such as lipid membranes and membrane proteins and continues with chapters devoted to the simulation and analysis of con...
Clinical Research in Private Practice
Clinical research is the tip of the spear for innovation and central in the development of improving safety and efficacy for patient centric care. Unfortunately, clinical research in academic practices is bogged down by inefficiency and infrequent regulatory oversight, thus leaving physicians unable to meet the clinical and research needs for driving innovation. Private practice is a valid practice cohort that can effectively, reliably, and reproducibly perform study related activities, for both...
This reference book on clinical experimentation focuses on principles that are especially useful in the design and analysis of studies on human subjects. It shows how to choose between modern and classical competing designs for a clinical study - such as crossover designs, multicenter studies, and repeated measure experiments - how to carry out each design and analyze the resulting data. The book provides many practical examples, end-of-chapter problems and references, and solutions to each prob...
Medical research has been central to biomedicine in Africa for over a century, and Africa, along with other tropical areas, has been crucial to the development of medical science. At present, study populations in Africa participate in an increasing number of medical research projects and clinical trials, run by both public institutions and private companies. Global debates about the politics and ethics of this research are growing and local concerns are prompting calls for social studies of th...
Handbook of Zoonoses, Second Edition, Section A
This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and preven...
Qualitative researchers have traditionally been cautious about claiming that their work was scientific. The "right-on" schools have exaggerated this caution into an outright rejection of science as a model for their work. Science is, for them, outmoded; "an archaic form of consciousness surviving for a while yet in a degraded form" (Tyler 1986:200). Scientists' assertions that they are in pursuit of truth simply camouflage their own lust for power. There is no essential difference between truth...