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This volume contains the Proceedings of the Special Seminar on: FRAGTALS held from October 9-15, 1988 at the Ettore Majorana Centre for Scientific Culture, Erice (Trapani), Italy. The concepts of self-similarity and scale invariance have arisen independently in several areas. One is the study of critical properites of phase transitions; another is fractal geometry, which involves the concept of (non-integer) fractal dimension. These two areas have now come together, and their methods have extend...

Molecular Modeling of Proteins, Second Edition provides a theoretical background of various methods available and enables non-specialists to apply methods to their problems by including updated chapters and new material not covered in the first edition. This detailed volume opens by featuring classical and advanced simulation methods as well as methods to set-up complex systems such as lipid membranes and membrane proteins and continues with chapters devoted to the simulation and analysis of con...

Plastics have occupied an important place in the modern medical industry. It has substituted traditional devices and products made of metal, other materials, and ceramics. Over recent years, increased reliance on transparent plastic pharmaceutical and medical products has produced remarkable breakthroughs that improve medical attention delivery and allow it to be more comfortable for the masses to live better and longer lives. The purpose of this handbook is to provide a strategic perspective on...

Clinical research is the tip of the spear for innovation and central in the development of improving safety and efficacy for patient centric care. Unfortunately, clinical research in academic practices is bogged down by inefficiency and infrequent regulatory oversight, thus leaving physicians unable to meet the clinical and research needs for driving innovation. Private practice is a valid practice cohort that can effectively, reliably, and reproducibly perform study related activities, for both...

This reference book on clinical experimentation focuses on principles that are especially useful in the design and analysis of studies on human subjects. It shows how to choose between modern and classical competing designs for a clinical study - such as crossover designs, multicenter studies, and repeated measure experiments - how to carry out each design and analyze the resulting data. The book provides many practical examples, end-of-chapter problems and references, and solutions to each prob...

This book provides a clear and thorough introduction to meta-analysis, the process of synthesizing data from a series of separate studies. Meta-analysis has become a critically important tool in fields as diverse as medicine, pharmacology, epidemiology, education, psychology, business, and ecology. Introduction to Meta-Analysis: Outlines the role of meta-analysis in the research processShows how to compute effects sizes and treatment effectsExplains the fixed-effect and random-effects models fo...

Since the last major compendium dedicated to cyclic nucleotide phosphodiesterases (PDEs) was published over 15 years ago, an enormous amount of progress has occurred in the field. There is great need for a centralized source for key information in this burgeoning and therapeutically important area of medical research. Cyclic Nucleotide Phosphodiesterases in Health and Disease provides an integrated volume covering PDE biology from genes to organisms. It examines phosphodiesterases as pharmacolo...

This multivolume handbook presents the most authoritative and comprehensive reference work on major zoonoses of the world. The Handbook of Zoonoses covers most diseases communicable to humans, as well as those diseases common to both animals and humans. It identifies animal diseases that are host specific and reviews the effects of various human diseases on animals. Discussions address diseases that remain important public and animal health problems and the techniques that can control and preven...

Practical immortality may be within our grasp, due to cutting-edge scientific research and amazing medical breakthroughs that are coming at an astonishing speed. In Chasing Life, prominent neurosurgeon and CNN Chief Medical Correspondent Dr Sanjay Gupta blends accounts of discoveries from around the world with advice for optimal health and longevity.For centuries, adventurers and scientists have believed that not only could we delay death but that 'practical immortality' was within our reach. To...

Medical research has been central to biomedicine in Africa for over a century, and Africa, along with other tropical areas, has been crucial to the development of medical science. At present, study populations in Africa participate in an increasing number of medical research projects and clinical trials, run by both public institutions and private companies. Global debates about the politics and ethics of this research are growing and local concerns are prompting calls for social studies of th...

This text provides researchers with descriptions and explanations of the concepts and methods used in qualitative research. With the move towards evidence-based practice and emphasis placed on multidisciplinary research teams, there is a growing use of qualitative research methods. Qualitative research looks at processes as well as outcomes and enables data to be gathered on a range of human experience, taking a person-centred and holistic approach. The book's entries are ordered alphabetically...