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The Taking Sides Collection on McGraw-Hill Create (TM) includes current controversial issues in a debate-style format designed to stimulate student interest and develop critical thinking skills. This Collection contains a multitude of current and classic issues to enhance and customize your course. You can browse the entire Taking Sides Collection on Create, or you can search by topic, author, or keywords. Each Taking Sides issues is thoughtfully framed with Learning Outcomes, an Issue Summary,...

Over the last decade the world has experienced a growing interest in problems associated with the nonmedical use of drugs. This interest has corresponded to a real growth in the extent, diversity, and social impact of the use of alcohol and drugs in many societies. As a result, the amount of research and writing on the subject of drug problems has greatly increased, and it has become very difficult for one individual to keep up with all the relevant literature. There is thus an acute need in the...

President Theodore Roosevelt once said, "Far and away the best prize that life offers is the chance to work hard at work worth doing." This quote is not only the source from which the title was borne, but also the philosophical approach toward TBI rehabilitation embraced by the 26 rehabilitation experts who wrote Work Worth Doing: Advances in Brain Injury Rehabilitation. This important, and possibly controversial, book of issues and methods addresses the full spectrum of vocational rehabilitatio...

The gas nitric oxide (NO) has burst upon neuroscience only recently, and yet it has permeated into almost every avenue of current research. The unique properties of this novel messenger have revolutionized our way ofthinking about neurotransmission. These special properties have also lead neuroscientists to invoke NO to explain many previously unexplained phenomena in neurobiology. Fortunately, the development of numerous pharmacological agents is now allowing thesehypotheses to be tested.This v...

General Description of the Volume:Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport. This volume plus its companion Volumes 255 and 256 cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecu...

Neoglycoconjugates are not only useful for the basic understanding of protein-carbohydrate interactions, but they have many practical applications as well. They are powerful reagents in many cell biology studies and excellent tools for the isolation and characterization of animal and plant lectins, separation of cells, as well as for the targeting of drugs, artificial vaccines, and diagnostic reagents. Volume 247 and its companion Volume 242 contain many practical methods on how to prepare and u...

In Beyond Prozac, Samuel Barondes explains the science underlying rational design of the next generation of antidepressive agents, and how we have learned what we know about the molecular basis of the neuropharmacological treatment of mood disorders. Barondes is a pioneer of molecular science, and he presents many case studies throughout the book to help readers understand the stakes and impact of mood disorders, and the scope of our current and potential abilities to intervene and mend clinica...

Steroid Hormone Action is a comprehensive overview of the molecular mechanisms by which these hormones regulate the expression of specific target genes. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid binding proteins and steroidogenesis. Steroid receptors represent one of the best characterized transcription factors so that the book will be of general interest to Molecular Biologists studying eucaryotic gene...

Self-awareness - the ability to recognize one's existence - is one of the most important variables in psychology. Without self-awareness, people would be unable to self-reflect, recognize differences between the self and others, or compare themselves with internalized standards. Social, clinical, and personality psychologists have recognized the significance of self-awareness in human functioning, and have conducted much research on how it participates in everyday life and in psychologica...

The Rat Nervous System provides a comprehensive description of the cytoarchitecture, chemoarchitecture, and connectivity of the rat nervous system. In addition it offers updated and supplemented information onthe following systems: peripheral motor, peripheral somatosensor, vascular, central motor, pain, and additional neurotransmitter systems.

This volume combines the classical fields of perception research with the major theoretical attitudes of today's research, distinguishing between experience - versus performance-related approaches, transformational versus interactional approaches, and approaches that rely on the processing versus discovery of information. Perception is separated into two parts. The first part deals with basic processes and mechanisms, and discusses early vision and later, yet still basic, vision. The second cove...

This book provides comprehensive coverage of the cytokines from a pharmacological approach. The chapters are presented in a consistent format allowing easy cross-reference, with sample diagrams and a summary table of essential facts for each chapter at the end of the book.Cytokines is unique in stressing cytokine biology and the application of research data to provide disease therapy. With 33 detailed and up-to-date chapters about individual cytokines, this comprehensive reference will provide b...