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An exploration of the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.

Uno de los mejores libros del Siglo XXI según el New York Times "Una magistral historia de la investigación sobre el cáncer" -Publishers Weekly Esta es la historia más compleja de una de las enfermedades más extendidas de nuestro tiempo una crónica completa del cáncer desde sus orígenes hasta los modernos tratamientos que han surgido gracias a un siglo de investigación, ensayos y pequeños avances trascendentales en muchos lugares distintos. Al mismo tiempo es una reflexión sobre la enfermedad,...

The past five years have witnessed a remarkable development of interest in cell death 'from inside out'. After 30 years of relative obscurity, its quantitative importance in the building and maintenance of normal tissues, the subtle strategies involved in its regulation, and its significance in the pathogenesis of diseases of major social importance are becoming clear. Moreover, because a distinct set of biological events is involved in this death, these events themselves become reason­ able tar...

This book provides a qualitative and quantitative exploration of the action of radiation on living matter which leads to a complete and coherent interpretation of radiation biology. It takes readers from radiation-induced molecular damage in the nucleus of the cell and links this damage to cellular effects such as cell killing, chromosome aberrations and mutations before exploring organ damage, organism lethality and cancer induction. It also deals with radiological protection concepts and the d...

NEW YORK TIMES BESTSELLER • “An inspiring story of coming back from cancer and learning to cherish every moment.”—People “I have breast cancer.” When Good Morning America anchor Amy Robach revealed her shocking diagnosis on live television in November 2013, the seasoned news reporter embarked on the most difficult and illuminating journey of her life. In this intimate memoir she retraces the twelve months following her announcement and speaks candidly, for the first time, about how her illness...

This handbook provides surgeons with updated information about the current status, perspectives and controversies for staging and treating cancer through minimal access procedures. The authors discuss the biology of minimal access, techniques, the equipment used, the perspectives and controversies surrounding the procedures in cancer management.

This book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targe...

Bladder cancer is one of the most common cancers - and one of the least discussed. But bladder cancer, like other kinds of cancer, will greatly change the life of anyone who has the disease. Learning to live with the challenge of bladder cancer means getting good medical care, building a support group, and gathering as much information as you can. In this large-print guide, Dr Mark Schoenberg and the faculty and staff of the Johns Hopkins Genitourinary Oncology Group tell you what you need to kn...

This is the first comprehensive book on Smad signal transduction. Forward looking reviews of Smads are provided in a series of 22 cutting-edge chapters. The book is written for an audience with basic understanding of molecular and cell biology. This volume provides an in-depth review of a rapidly developing field and extensive cross-references between chapters are provided.

With the exception of cancer of the breast, thyroid and melanoma, all cancers are commoner in men than in women. Cancer of the bladder is nearly four times as common in men; lung cancer is three and a half times as common; stomach cancer is two and a half times as common; mouth, gullet and kidney cancers are twice as common; and colorectal, pancreas, brain, lymph and various other cancers are one and a half times as common. Being a man could seriously damage your health unless we recognise the r...