Failure to adequately control any microbial challenge associated within process or product by robust sterilisation will result in a contaminated marketed product, with potential harm to the patient. Sterilisation is therefore of great importance to healthcare and the manufacturers of medical devices and pharmaceuticals. Sterility, sterilisation and sterility assurance for pharmaceuticals examines different means of rendering a product sterile by providing an overview of sterilisation methods inc...
Medical Risk Prediction Models (Chapman & Hall/CRC Biostatistics)
by Thomas A. Gerds and Michael W. Kattan
Medical Risk Prediction Models: With Ties to Machine Learning is a hands-on book for clinicians, epidemiologists, and professional statisticians who need to make or evaluate a statistical prediction model based on data. The subject of the book is the patient’s individualized probability of a medical event within a given time horizon. Gerds and Kattan describe the mathematical details of making and evaluating a statistical prediction model in a highly pedagogical manner while avoiding mathematica...
Mendelian Randomization (Chapman & Hall/CRC Interdisciplinary Statistics)
by Stephen Burgess and Simon G. Thompson
Mendelian Randomization: Methods For Causal Inference Using Genetic Variants provides thorough coverage of the methods and practical elements of Mendelian randomization analysis. It brings together diverse aspects of Mendelian randomization from the fields of epidemiology, statistics, genetics, and bioinformatics. Through multiple examples, the first part of the book introduces the reader to the concept of Mendelian randomization, showing how to perform simple Mendelian randomization investigat...
Measurement Theory and Practice (Kendall's Library of Statistics)
by David Hand
We live in a world of measurements. Measurements, be they of length, speed, weight, temperature, intelligence, income, endurance, greed, gross domestic product, quality of life, unemployment or skill at a job, are all numerical manifestations of the extent of some underlying attribute. They reflect the reality around us -- length and weight provide examples of systems that represent clear physical attributes. At the same time, measurements also define the reality around us -- psychometric tests...
The anthrax envelopes incident in the United States in 2001 created the impetus for a substantial increase in preparedness for bioterrorist threats among both public health and law enforcement professionals, worldwide. Ever increasing resources are now being allocated for dealing with a wide variety of potential threats, from the reintroduction of eradicated viruses such as smallpox to the possibility of genetically engineered novel pathogens. Despite the potentially devastating consequences of...
The Epigenome and Developmental Origins of Health and Disease
Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero envi...
Biological Clocks
The emerging discipline denominated "chronoecology of behaviour" is the result of the interaction between the work of behavioural ecologists and chronobiologists -- those who explain biological rhythms on the basis of experimental studies carried out in the laboratory. Since the beginning of this century, this interaction has generated interest in understanding how biological rhythms behave in organisms living in their natural habitat. This approach requires field studies of rest/activity rhythm...
Death and Disease in South-east Asia (Asian Studies Association of Australia (ASAA) S.)
by Norman G. Owen
From a 'decoding' of ancient Balinese myths to the careful computation of mortality rates for the modern Philippines, these essays extend our understanding of South-east Asian history.
The human species faces a new kind of threat to its health - perhaps to its longer-term survival. Burgeoning numbers, consumption and the spread of technology are overloading Earth's capacity to replenish and repair itself. This eloquent and alarming book examines the likely impact on human health of the ongoing degradation of the planet's ecosystems. Where most studies of these phenomena have limited their analysis to the environmental consequences, A. J. McMichael brings a broader evolutionary...
A New York Times reporter's eye-opening call to arms in the fight against epidemic diseases We face a great choice. Philip Hilts, a prizewinning journalist for the New York Times and the Washington Post, argues in this report on global epidemic diseases that the world's leading nations now have the means to win the fight against "the coming plague"—but they must act quickly or face grave consequences. Based on firsthand visits to disease hot spots around the world and in-depth interviews wi...
The book provides an accessible but comprehensive overview of methods for mediation and interaction. There has been considerable and rapid methodological development on mediation and moderation/interaction analysis within the causal-inference literature over the last ten years. Much of this material appears in a variety of specialized journals, and some of the papers are quite technical. There has also been considerable interest in these developments from empirical researchers in the social and...
What If We Do Nothing?: AIDS and other Epidemics (What If We Do Nothing?)
by Carol Ballard
At last - a new edition of the highly acclaimed book Clinical Trials in Psychiatry This book provides a concise but thorough overview of clinical trials in psychiatry, invaluable to those seeking solutions to numerous problems relating to design, methodology and analysis of such trials. Practical examples and applications are used to ground theory whenever possible. The Second Edition includes new information regarding:* Recent important psychiatric trials* More specific discussion of psychiatry...
When worries and fears come along, Harley the Hedgehog can handle them—and so can your child! A fun activity book for coping with anxiety, for kids ages 5 to 9. Expert psychologist and best-selling author Dr. Regine Galanti offers an activity book that teaches kids how to be brave and feel less anxious. All children get anxious sometimes. For some kids, though, anxiety can become something bigger and more intrusive, stopping them from enjoying friends, family, activities, sports, or school. Th...
Focus on Bioterrorism
The anthrax murders in the U.S. and discoveries of biological weapon plans in Africa served as a wake-up call (too late as usual) that biological weapons might actually be a weapon of mass destruction. Their small size but highly deadly nature adds to the fear factor. The reality of this potential danger to the U.S. population found both the federal government as well as state government clueless. This book presents analyses of the actions planned or already carried out in the battle against the...
In this first volume, Professor Greenberg offers to epidemiologists, medical entomologists, microbiologists, parasitologists, and others concerned with public health and synanthropic and interspecies relationships, a definitive reference work based upon a comprehensive review of the vast studies undertaken during the past 50 years.Originally published in 1971.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the dis...
Disease Ecology
Many infectious diseases of recent concern, including malaria, cholera, plague, and Lyme disease, have emerged from complex ecological communities, involving multiple hosts and their associated parasites. Several of these diseases appear to be influenced by human impacts on the environment, such as intensive agriculture, clear-cut forestry, and habitat loss and fragmentation; such environmental impacts may affect many species that occur at trophic levels below or above the hostcommunity. These o...
A provocative book arguing that the workplace is where we learn to live democratically. In The Pandemic Workplace, anthropologist Ilana Gershon turns her attention to the US workplace and how it changed—and changed us—during the pandemic. She argues that the unprecedented organizational challenges of the pandemic forced us to radically reexamine our attitudes about work and to think more deeply about how values clash in the workplace. These changes also led us as workers to engage more with th...
Germs Gone Wild: How the Unchecked Development of Bio-Defense Threatens America
by Kenneth King